ID   ATG17_ASPCL             Reviewed;         557 AA.
AC   A1C7E5;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Autophagy-related protein 17;
GN   Name=atg17; ORFNames=ACLA_073510;
OS   Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS   NRRL 1 / QM 1276 / 107).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=344612;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1;
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- FUNCTION: Autophagy-specific protein that functions in response to
CC       autophagy-inducing signals as a scaffold to recruit other ATG proteins
CC       to organize pre-autophagosomal structure (PAS) formation. Modulates the
CC       timing and magnitude of the autophagy response, such as the size of the
CC       sequestering vesicles. Plays particularly a role in pexophagy and
CC       nucleophagy (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Preautophagosomal
CC       structure membrane {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATG17 family. {ECO:0000305}.
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DR   EMBL; DS027045; EAW14316.1; -; Genomic_DNA.
DR   RefSeq; XP_001275742.1; XM_001275741.1.
DR   AlphaFoldDB; A1C7E5; -.
DR   SMR; A1C7E5; -.
DR   STRING; 5057.CADACLAP00006480; -.
DR   EnsemblFungi; EAW14316; EAW14316; ACLA_073510.
DR   GeneID; 4707887; -.
DR   KEGG; act:ACLA_073510; -.
DR   VEuPathDB; FungiDB:ACLA_073510; -.
DR   eggNOG; ENOG502RYHP; Eukaryota.
DR   HOGENOM; CLU_028356_0_0_1; -.
DR   OMA; SSINHVW; -.
DR   OrthoDB; 1496047at2759; -.
DR   Proteomes; UP000006701; Unassembled WGS sequence.
DR   GO; GO:0034045; C:phagophore assembly site membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000422; P:autophagy of mitochondrion; IEA:UniProt.
DR   InterPro; IPR007240; Atg17.
DR   InterPro; IPR045326; ATG17-like_dom.
DR   PANTHER; PTHR28005; PTHR28005; 1.
DR   Pfam; PF04108; ATG17_like; 1.
PE   3: Inferred from homology;
KW   Autophagy; Coiled coil; Cytoplasm; Membrane; Reference proteome.
FT   CHAIN           1..557
FT                   /note="Autophagy-related protein 17"
FT                   /id="PRO_0000317979"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          204..227
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          495..532
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          334..355
FT                   /evidence="ECO:0000255"
FT   COILED          428..458
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   557 AA;  61445 MW;  46BD213A0CEBA9D6 CRC64;
     MSSSESSSAS GGGPPDAEPS QTEQQTMPQL DTLISHLVAA KRSLSSINHV WRANEIVTTA
     RAALEESVVV SARTGFLRRG LNNQLRLLYS VRTEVEEISL RGRSEFAAVL KDLDAADARL
     RRTLELLRET IVHGGFRPEG EQPRSLHDFV DERGVEELHA ALKNSIDRTN GAQAQLDSSN
     HAFDDELLSI KEALGNYRAV AKLASSRSSS SPSSSSASNS SLPSMSSMPS MLHSLEMHAQ
     EMANLLESLV RHFDLCVTAV KHTEGGGAAA KSITGDMHVG VNASGRIGPN IEEGINANLN
     APLDPLSDSE YREMVHVLIK DATEAEDVVM EIHDRIGEME SSLENVLAQR DALRSIYNAT
     IDVFQHLSSL ASTRLPGYIA QAHDFTRVWH EENDRIAGGL DDLAHLNSFY DGFLDAYDGL
     IIEVARRRHV RQRVEKVLRD AKHKLDQLYE EDVNAREAFR VEKGDYLPSD IWPEVGREPM
     RIEFRRILGG KVKGAVSEQA NDEEPTAGER EQRGGGQENH LSAVGDNTEV DEVIPELPRD
     LVEQVFARIQ TRVKSTT