PRM1_LACBS
ID PRM1_LACBS Reviewed; 1026 AA.
AC B0D0P0;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 20-MAY-2008, sequence version 2.
DT 03-AUG-2022, entry version 46.
DE RecName: Full=Plasma membrane fusion protein PRM1;
GN Name=PRM1; ORFNames=LACBIDRAFT_231982;
OS Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver)
OS (Laccaria laccata var. bicolor).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Tricholomataceae; Laccaria.
OX NCBI_TaxID=486041;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 / ATCC MYA-4686;
RX PubMed=18322534; DOI=10.1038/nature06556;
RA Martin F., Aerts A., Ahren D., Brun A., Danchin E.G.J., Duchaussoy F.,
RA Gibon J., Kohler A., Lindquist E., Pereda V., Salamov A., Shapiro H.J.,
RA Wuyts J., Blaudez D., Buee M., Brokstein P., Canbaeck B., Cohen D.,
RA Courty P.E., Coutinho P.M., Delaruelle C., Detter J.C., Deveau A.,
RA DiFazio S., Duplessis S., Fraissinet-Tachet L., Lucic E., Frey-Klett P.,
RA Fourrey C., Feussner I., Gay G., Grimwood J., Hoegger P.J., Jain P.,
RA Kilaru S., Labbe J., Lin Y.C., Legue V., Le Tacon F., Marmeisse R.,
RA Melayah D., Montanini B., Muratet M., Nehls U., Niculita-Hirzel H.,
RA Oudot-Le Secq M.P., Peter M., Quesneville H., Rajashekar B., Reich M.,
RA Rouhier N., Schmutz J., Yin T., Chalot M., Henrissat B., Kuees U.,
RA Lucas S., Van de Peer Y., Podila G.K., Polle A., Pukkila P.J.,
RA Richardson P.M., Rouze P., Sanders I.R., Stajich J.E., Tunlid A.,
RA Tuskan G., Grigoriev I.V.;
RT "The genome of Laccaria bicolor provides insights into mycorrhizal
RT symbiosis.";
RL Nature 452:88-92(2008).
CC -!- FUNCTION: Involved in cell fusion during mating by stabilizing the
CC plasma membrane fusion event. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PRM1 family. {ECO:0000305}.
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DR EMBL; DS547095; EDR11496.1; ALT_TERM; Genomic_DNA.
DR RefSeq; XP_001877393.1; XM_001877358.1.
DR AlphaFoldDB; B0D0P0; -.
DR STRING; 486041.B0D0P0; -.
DR EnsemblFungi; EDR11496; EDR11496; LACBIDRAFT_231982.
DR GeneID; 6073481; -.
DR KEGG; lbc:LACBIDRAFT_231982; -.
DR HOGENOM; CLU_010191_2_0_1; -.
DR InParanoid; B0D0P0; -.
DR OrthoDB; 1333210at2759; -.
DR Proteomes; UP000001194; Unassembled WGS sequence.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0043332; C:mating projection tip; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR026777; PRM1.
DR PANTHER; PTHR31030; PTHR31030; 1.
PE 3: Inferred from homology;
KW Cell membrane; Conjugation; Glycoprotein; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..1026
FT /note="Plasma membrane fusion protein PRM1"
FT /id="PRO_0000337283"
FT TOPO_DOM 1..26
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 48..108
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 130..300
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 301..321
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 322..403
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 404..424
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 425..611
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 612..632
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 633..1026
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT REGION 693..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 793..812
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 818..879
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 904..952
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 696..715
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 760..777
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 825..874
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 212
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 227
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 256
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 265
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 458
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 463
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 492
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 499
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 518
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 560
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 1026 AA; 112212 MW; 4058390602A4E239 CRC64;
MSTLAQPPTY DATTTADTQL TPYLQLSHLL SLTWLAYPIL SLIFVAFRLQ LSMTSLENSI
LSVKSDILSS CKAAEHAATA AASMPRYMAL ATNEQFADAV NGSLHAARVA LVVSLTAMEA
IINFIIDTYR STFFCFLELV VTGGLAVLIS AVQGINTVLQ SVTGSLRTSI QSDIASANSV
IQNAINAINK VNPFGNINAP QIAVPSLDAL QNVTLPASFQ DALTSLNASI PTVADLKGAL
ESIIDTPFEL LKTDINDTFT GLSFNSSILP VPEQNRLSFC NDVDLSVIDE IGRDFIKIAK
IGVVIIILLA LLLIGFNCLL TWYKWRCMKR HLEYTRQAWN TDPTMIHTKT SSSSPPQVIL
TDHNLMILHA NSAHPLITRI MNQLSARLRF SPSHHTNLRW FLHYIFHAPA LACFLIGFFG
LLSVEIQLLA MGPIVHKFED SAAAAVSDFS NVIAASINDS MFNQSALYAN DINSRVDVIQ
STINNGVFGW VNSTTFTLNA TINAFYTDIQ KAVSTVFNGT VLESPANDFI KCFIGGKVDA
IENALTFLHD NLQIDIPRVN DSILVLSPAS VHEATAPIAA AAIGGGPNDK EGLIGRLVKA
YTATLKKERV MFGLFLALWG IVVLMGVCIL IWNTYGQALL KKRRRRRYEL EQRSGINGIV
VPFRSGVESE NEKGAVLDLP SFTPLPSPRR SAFKPFWGSR SNSPMGNQPS GSAESFAIQK
EEWDDFPPKP IESTVKKPSR LMAIGRKAMG KERVKADGGE ESTSSSSEKS PSDEGIRSTT
WVGKFTTLWT KKEPVPQSSE FWDQPSRGRP KLQINVHRDS ADAGPNLYSS HTMQSRWSAS
PDATQTSWGK VMSPSKKTST TTTATFQTPF GYSTRKSGVP IHDLDQSYDS LSSKSGAPAS
LPLPLYHGFS GSQSRPSARA EATTTERKDT SPPPPFAPYR TNKLPNPPYD EQRRTSTLRV
MNPTFKSSDH TVAMPASRLL TTMDARHSSA INPFITPFDD EHRVTIDNNP VYVRQSIPTN
PFGVAL
