PRM1_SCHPO
ID PRM1_SCHPO Reviewed; 703 AA.
AC Q9P771;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Plasma membrane fusion protein prm1;
GN Name=prm1; ORFNames=SPAP7G5.03;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Involved in cell fusion during mating by stabilizing the
CC plasma membrane fusion event. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PRM1 family. {ECO:0000305}.
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DR EMBL; CU329670; CAB88270.1; -; Genomic_DNA.
DR RefSeq; NP_594313.1; NM_001019736.2.
DR AlphaFoldDB; Q9P771; -.
DR SMR; Q9P771; -.
DR BioGRID; 279248; 3.
DR STRING; 4896.SPAP7G5.03.1; -.
DR TCDB; 9.B.63.1.2; the yeast pheromone-induced plasma membrane mating cell fusion protein (prm1) family.
DR iPTMnet; Q9P771; -.
DR PaxDb; Q9P771; -.
DR EnsemblFungi; SPAP7G5.03.1; SPAP7G5.03.1:pep; SPAP7G5.03.
DR GeneID; 2542800; -.
DR KEGG; spo:SPAP7G5.03; -.
DR PomBase; SPAP7G5.03; prm1.
DR VEuPathDB; FungiDB:SPAP7G5.03; -.
DR eggNOG; ENOG502QRP5; Eukaryota.
DR HOGENOM; CLU_010191_1_0_1; -.
DR InParanoid; Q9P771; -.
DR OMA; QTYLCLF; -.
DR PhylomeDB; Q9P771; -.
DR PRO; PR:Q9P771; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0005887; C:integral component of plasma membrane; ISO:PomBase.
DR GO; GO:0043332; C:mating projection tip; IDA:PomBase.
DR GO; GO:0032220; P:plasma membrane fusion involved in cytogamy; IMP:PomBase.
DR GO; GO:0097036; P:regulation of plasma membrane sterol distribution; IMP:PomBase.
DR InterPro; IPR026777; PRM1.
DR PANTHER; PTHR31030; PTHR31030; 1.
PE 3: Inferred from homology;
KW Cell membrane; Conjugation; Glycoprotein; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..703
FT /note="Plasma membrane fusion protein prm1"
FT /id="PRO_0000337289"
FT TOPO_DOM 1..14
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 36..102
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 103..123
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 124..285
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 286..306
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 307..375
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 376..396
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 397..566
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 567..587
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 588..703
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT CARBOHYD 142
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 185
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 196
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 221
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 244
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 256
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 423
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 430
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 453
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 459
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 470
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 510
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 530
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 542
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 545
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 566
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 703 AA; 78740 MW; B6925C68B6BC3DA0 CRC64;
MASSYLSLAA RLSQCWISPW SLCCLYILMQ FFLFTKDLNT KIGDFVNDEQ ATCNYIQEKV
DILLDSPSLI ANAAVRVAKD GIQSTVKIIL SGISDSLIAA ENVFIFFIEF SYGTYLCLIQ
LAIDGILDAV ADVGEEIGTA VNDTLHAIAD EIEDTVSSLN EVFQSAEDSL EKVASWLGED
INLPNVSIPE IQSLRNFTLS SSYDTEFEKL KAGVNFDSAI NATKAAISKP FSSARNLILE
KVSNYSFDTS MVSSPNKTHV VVCSTDDLTA ISSFILSSIY KIRKVVIISL LIIIAGLFLI
SSIYEIWKWC RIRHKAFLLD EHIRSNKFED TRDLISYIES PISWNLKYFI SALPLPCFLS
VQLRWFITYI FHPPAAMILF ISCTSFISGI LQLVLLNNIR EDGSVISALA QNSFHKVESA
LANVSVAWAN STNQIILKNQ ENINNNMFGS IHNTTLSLNS TLNTFMNELN SSMTSAFGDT
FLASTVQNVM NCLLYRKIEN FEEVLTWVYN KSHIELPLLP TDILSKSIDN QTIYSSLYSS
LNSSNSTVSF SGIFDRVEKS VISELNFSFL FFLLWLLICA FGLIGVLSSW LKSLFLSLLD
LVIPNPKENI TLPVQSLAFP VTKSCRPPPI PPRESHVYDF QNFQYEEDDC IDYKRSLGLI
SLSSDLAIDI PISPAIISDI QFNSITTESE ETTYLLKEKQ DRY
