ID   ATG17_ASPTN             Reviewed;         550 AA.
AC   Q0CY33;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Autophagy-related protein 17;
GN   Name=atg17; ORFNames=ATEG_01401;
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=341663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIH 2624 / FGSC A1156;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA   Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA   Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Autophagy-specific protein that functions in response to
CC       autophagy-inducing signals as a scaffold to recruit other ATG proteins
CC       to organize pre-autophagosomal structure (PAS) formation. Modulates the
CC       timing and magnitude of the autophagy response, such as the size of the
CC       sequestering vesicles. Plays particularly a role in pexophagy and
CC       nucleophagy (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Preautophagosomal
CC       structure membrane {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATG17 family. {ECO:0000305}.
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DR   EMBL; CH476595; EAU38158.1; -; Genomic_DNA.
DR   RefSeq; XP_001208766.1; XM_001208766.1.
DR   AlphaFoldDB; Q0CY33; -.
DR   SMR; Q0CY33; -.
DR   STRING; 341663.Q0CY33; -.
DR   EnsemblFungi; EAU38158; EAU38158; ATEG_01401.
DR   GeneID; 4316260; -.
DR   VEuPathDB; FungiDB:ATEG_01401; -.
DR   eggNOG; ENOG502RYHP; Eukaryota.
DR   HOGENOM; CLU_028356_0_0_1; -.
DR   OMA; SSINHVW; -.
DR   OrthoDB; 1496047at2759; -.
DR   Proteomes; UP000007963; Unassembled WGS sequence.
DR   GO; GO:0034045; C:phagophore assembly site membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000422; P:autophagy of mitochondrion; IEA:UniProt.
DR   InterPro; IPR007240; Atg17.
DR   InterPro; IPR045326; ATG17-like_dom.
DR   PANTHER; PTHR28005; PTHR28005; 1.
DR   Pfam; PF04108; ATG17_like; 1.
PE   3: Inferred from homology;
KW   Autophagy; Coiled coil; Cytoplasm; Membrane; Reference proteome.
FT   CHAIN           1..550
FT                   /note="Autophagy-related protein 17"
FT                   /id="PRO_0000317982"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          205..224
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          491..531
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          315..344
FT                   /evidence="ECO:0000255"
FT   COILED          427..457
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        495..526
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   550 AA;  60296 MW;  90890591C28164A7 CRC64;
     MSASESSATS SVAPHDHGSS QVETSIPQLE TLISHLVAAK RSLSSINHVW RANEIVTSAR
     SALEESVVVS ARTGFLRKGL NNQLRLLYSV RAEVEEVSVR GRSEFAGVLR SLDAADARLR
     KTLNLLRETI VHASFRPEGE EPKSLHDFVD ERGVEELNSA LKSAIDRTNA AQTELETSNC
     AFDDELQSIK EALGNYRAVT KMASSRTSAS SSSSSASNAS LPSMSGVPSM LHSLEMHAQE
     MANLLESLVR HFDLCVTAVK HTEGGGAAAR SITGDMPAGM NVSGRGGPNI EEGINANLNA
     PLDPLSNSEY REMVNVLIKD AAEAEDVVME IQDRIGEMES IYENILGQRD AVLAVYNATT
     SVFEHISSLA SARLAGYIAQ AHTFTRVWND EHEHIQGGLS DLSDLNTLYD GFLEAYDGLI
     LEVARRRHVR QRVEKVLRDA KHKLDQLYEE DVNARETFRV EQGDYLPSDI WPGIGREPMR
     IEFRRISGGT LKGVQDQHPD EDTAPPSDPK DVANHTTDEN RDEGETIPAL PKALVEEALA
     RLKARNRQAT