ID   PRM3_BOVIN              Reviewed;          93 AA.
AC   Q32PA2;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Protamine-3;
DE   AltName: Full=Sperm protamine P3;
GN   Name=PRM3;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the protamine P3 family. {ECO:0000305}.
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DR   EMBL; BC108198; AAI08199.1; -; mRNA.
DR   RefSeq; NP_001071521.1; NM_001078053.2.
DR   AlphaFoldDB; Q32PA2; -.
DR   STRING; 9913.ENSBTAP00000017347; -.
DR   PaxDb; Q32PA2; -.
DR   Ensembl; ENSBTAT00000017347; ENSBTAP00000017347; ENSBTAG00000013051.
DR   GeneID; 615629; -.
DR   KEGG; bta:615629; -.
DR   CTD; 58531; -.
DR   VEuPathDB; HostDB:ENSBTAG00000013051; -.
DR   VGNC; VGNC:33347; PRM3.
DR   eggNOG; ENOG502T3TU; Eukaryota.
DR   GeneTree; ENSGT00390000001558; -.
DR   HOGENOM; CLU_2398985_0_0_1; -.
DR   InParanoid; Q32PA2; -.
DR   OMA; RCAKLNT; -.
DR   OrthoDB; 1628050at2759; -.
DR   Proteomes; UP000009136; Chromosome 25.
DR   Bgee; ENSBTAG00000013051; Expressed in semen and 30 other tissues.
DR   ExpressionAtlas; Q32PA2; baseline.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0030317; P:flagellated sperm motility; IBA:GO_Central.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR026077; PRMP3.
DR   PANTHER; PTHR14317; PTHR14317; 1.
PE   3: Inferred from homology;
KW   Chromosome; Developmental protein; Differentiation; DNA condensation;
KW   DNA-binding; Nucleosome core; Nucleus; Phosphoprotein; Reference proteome;
KW   Spermatogenesis.
FT   CHAIN           1..93
FT                   /note="Protamine-3"
FT                   /id="PRO_0000261157"
FT   REGION          1..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        35..56
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         85
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q64256"
SQ   SEQUENCE   93 AA;  10140 MW;  60CC92AA23D04FE0 CRC64;
     MGSRCAKLGT GHGRGHESSM KKLVACVSQD NFSLSSEGEE EEEGEEEEEE EGEEEELPVQ
     GKLLLMEAGQ QEEGAEDADS EVQQSPEPKQ TRS