ID   ATG17_CANGA             Reviewed;         409 AA.
AC   Q6FPD4;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Autophagy-related protein 17;
GN   Name=ATG17; OrderedLocusNames=CAGL0J04686g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Autophagy-specific protein that functions in response to
CC       autophagy-inducing signals as a scaffold to recruit other ATG proteins
CC       to organize pre-autophagosomal structure (PAS) formation. Modulates the
CC       timing and magnitude of the autophagy response, such as the size of the
CC       sequestering vesicles. Plays particularly a role in pexophagy and
CC       nucleophagy (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Preautophagosomal
CC       structure membrane {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATG17 family. {ECO:0000305}.
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DR   EMBL; CR380956; CAG60859.1; -; Genomic_DNA.
DR   RefSeq; XP_447910.1; XM_447910.1.
DR   AlphaFoldDB; Q6FPD4; -.
DR   SMR; Q6FPD4; -.
DR   STRING; 5478.XP_447910.1; -.
DR   EnsemblFungi; CAG60859; CAG60859; CAGL0J04686g.
DR   GeneID; 2889451; -.
DR   KEGG; cgr:CAGL0J04686g; -.
DR   CGD; CAL0133050; ATG17.
DR   VEuPathDB; FungiDB:CAGL0J04686g; -.
DR   eggNOG; ENOG502QQDW; Eukaryota.
DR   HOGENOM; CLU_051526_0_0_1; -.
DR   InParanoid; Q6FPD4; -.
DR   OMA; YLPENIW; -.
DR   Proteomes; UP000002428; Chromosome J.
DR   GO; GO:1990316; C:Atg1/ULK1 kinase complex; IEA:EnsemblFungi.
DR   GO; GO:0034045; C:phagophore assembly site membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0120095; C:vacuole-isolation membrane contact site; IEA:EnsemblFungi.
DR   GO; GO:0060090; F:molecular adaptor activity; IEA:EnsemblFungi.
DR   GO; GO:0030295; F:protein kinase activator activity; IEA:EnsemblFungi.
DR   GO; GO:0000149; F:SNARE binding; IEA:EnsemblFungi.
DR   GO; GO:0000422; P:autophagy of mitochondrion; IEA:EnsemblFungi.
DR   GO; GO:0030242; P:autophagy of peroxisome; IEA:EnsemblFungi.
DR   GO; GO:0044805; P:late nucleophagy; IEA:EnsemblFungi.
DR   GO; GO:0034727; P:piecemeal microautophagy of the nucleus; IEA:EnsemblFungi.
DR   GO; GO:2000786; P:positive regulation of autophagosome assembly; IEA:EnsemblFungi.
DR   GO; GO:0045772; P:positive regulation of autophagosome size; IEA:EnsemblFungi.
DR   GO; GO:0034497; P:protein localization to phagophore assembly site; IEA:EnsemblFungi.
DR   InterPro; IPR007240; Atg17.
DR   InterPro; IPR045326; ATG17-like_dom.
DR   PANTHER; PTHR28005; PTHR28005; 1.
DR   Pfam; PF04108; ATG17_like; 1.
PE   3: Inferred from homology;
KW   Autophagy; Cytoplasm; Membrane; Reference proteome.
FT   CHAIN           1..409
FT                   /note="Autophagy-related protein 17"
FT                   /id="PRO_0000124558"
SQ   SEQUENCE   409 AA;  47978 MW;  3C2F69D2533847A1 CRC64;
     MPESLAERAR STLLKAQVLC REVESRIAEV KDRLSQWEKN RHTLRFLVSC LEHQLGFLEQ
     CALRQGIGRA LIETEWSQVV LVDLVNEMKL WYDKIQLRLE RLDQVENILV ADNKHLSHYI
     SQEQALVLKK RLDEVPIIRP QIENIQTQYD TMCKRVRQKL INKRLTEIKT IFDSQFGDEL
     TETAELTEVK PRDLDSIELE LVDYINSLTD HFDKCQALEK GLFNDSNEYD ELLKIVSADD
     SQLDDIMKHL LNTIDSTNHQ IDKVYEILDI KTKQKTILHG KINELIANCT KYSEYLAIFK
     GIATSIEKFK EGCMQDIQLT KELYKFYDEF ENSYNKLLQE VQRRRALSQK MLGIIKNCEN
     ELKTLHDEDQ KLRTHFLSEN GAFLPETIWP GEIDDLSPLY ALDYHIKEI