ID   ATG17_DEBHA             Reviewed;         487 AA.
AC   Q6BSK5;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Autophagy-related protein 17;
GN   Name=ATG17; OrderedLocusNames=DEHA2D08162g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Autophagy-specific protein that functions in response to
CC       autophagy-inducing signals as a scaffold to recruit other ATG proteins
CC       to organize pre-autophagosomal structure (PAS) formation. Modulates the
CC       timing and magnitude of the autophagy response, such as the size of the
CC       sequestering vesicles. Plays particularly a role in pexophagy and
CC       nucleophagy (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Preautophagosomal
CC       structure membrane {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATG17 family. {ECO:0000305}.
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DR   EMBL; CR382136; CAG86961.2; -; Genomic_DNA.
DR   RefSeq; XP_458815.2; XM_458815.1.
DR   AlphaFoldDB; Q6BSK5; -.
DR   SMR; Q6BSK5; -.
DR   STRING; 4959.XP_458815.2; -.
DR   EnsemblFungi; CAG86961; CAG86961; DEHA2D08162g.
DR   GeneID; 2901591; -.
DR   KEGG; dha:DEHA2D08162g; -.
DR   VEuPathDB; FungiDB:DEHA2D08162g; -.
DR   eggNOG; ENOG502RW77; Eukaryota.
DR   HOGENOM; CLU_565132_0_0_1; -.
DR   InParanoid; Q6BSK5; -.
DR   OMA; QCMKAVE; -.
DR   OrthoDB; 1496047at2759; -.
DR   Proteomes; UP000000599; Chromosome D.
DR   GO; GO:0034045; C:phagophore assembly site membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000422; P:autophagy of mitochondrion; IEA:UniProt.
DR   InterPro; IPR007240; Atg17.
DR   InterPro; IPR045326; ATG17-like_dom.
DR   PANTHER; PTHR28005; PTHR28005; 1.
DR   Pfam; PF04108; ATG17_like; 1.
PE   3: Inferred from homology;
KW   Autophagy; Cytoplasm; Membrane; Reference proteome.
FT   CHAIN           1..487
FT                   /note="Autophagy-related protein 17"
FT                   /id="PRO_0000124559"
SQ   SEQUENCE   487 AA;  56482 MW;  4C481D3E88E41F79 CRC64;
     MSSGVDRDTV ISWSEQAQTT LQEAKKMCTR AQASLQSTTY QLVTQLPERL QFVTFMVDAL
     KQQHELLTSI VESQSRIRKE SVSQFNVQVE RDLTPALAEL DDILARLAKA KVPSYLINNV
     VHELEVHIDT LVEDRNLCDF ISMDDIKLLT TNIEIYKANC TKLHGLLEKT MNESVIEPYQ
     IIALKKYHNI MKQYKELMPV QLGMNLAPDV SPYKLNNLIN TILKENSSLE HELVPMLEMM
     TNHYDQCVQG TLFFNTKNPK DPSGDVNFEV LRNDALELPD VLKELNTVYD IIVNNEVRTK
     KLLSSEFSRI DSLISMIKDL LEFYTDYKAT HLSKYMILVL SCDEIFGKCS IAMNSNQTPL
     EAYIETITSL SYHYTQFLSI YKSEYLTELF YEQYTYPRKY LAKLTDFLNN DMFHLQQEEY
     ERRKNWLARY GEFIPNEFKL PGELNQPSII QVVTEGLDDV QKDYNDGKFN ESAEEINLSD
     LIKTMKL