ID   AAAP_ANAML              Reviewed;         364 AA.
AC   Q5SF94;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 25.
DE   RecName: Full=Appendage-associated protein;
DE   Flags: Precursor;
GN   Name=aaaP {ECO:0000312|EMBL:AAS83466.1};
OS   Anaplasma marginale (strain Illinois).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Anaplasma.
OX   NCBI_TaxID=403778;
RN   [1] {ECO:0000305, ECO:0000312|EMBL:AAS83466.1}
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=15557651; DOI=10.1128/iai.72.12.7257-7264.2004;
RA   Stich R.W., Olah G.A., Brayton K.A., Brown W.C., Fecheimer M.,
RA   Green-Church K., Jittapalapong S., Kocan K.M., McGuire T.C.,
RA   Rurangirwa F.R., Palmer G.H.;
RT   "Identification of a novel Anaplasma marginale appendage-associated protein
RT   that localizes with actin filaments during intraerythrocytic infection.";
RL   Infect. Immun. 72:7257-7264(2004).
CC   -!- FUNCTION: Associates with actin filament appendages that are formed in
CC       the inclusion appendages of the parasitophorous vacuole during
CC       infection of the host erythrocyte. {ECO:0000269|PubMed:15557651}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15557651}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY514452; AAS83466.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q5SF94; -.
DR   GO; GO:0020003; C:symbiont-containing vacuole; IDA:UniProtKB.
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0051701; P:biological process involved in interaction with host; IDA:UniProtKB.
PE   4: Predicted;
KW   Coiled coil; Secreted; Signal.
FT   SIGNAL          1..?
FT                   /evidence="ECO:0000305"
FT   CHAIN           ?..364
FT                   /note="Appendage-associated protein"
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000258016"
FT   COILED          142..196
FT                   /evidence="ECO:0000255"
FT   COILED          288..313
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   364 AA;  39832 MW;  35CD8E1A8679EA83 CRC64;
     MGCPVSRGGS PGCGRRIAEE LRFFVVDREA SMCGDSCNGG GDRQQRQELA AAARASLLCL
     GGVMQQHITA AKARAELRKE LDAIDAEWRP VIARESLRKE LKAIDAQWQH AITFLRISRA
     IVVSIELSKE LKAIDAGWEP VIIHEAQKKK REREERVAQV RRELRAELRA IDAEWRLVIA
     RESLRKELDA IDAECRHTIK LRSALRAIEG RMELSKELKA IDAEWRPAIR LESAYRAIIG
     SIELSKELKA IDAETQHAVE LRRALRTIEG RIELSRELKA IDAEWAPRIA QAELAAAADA
     LKRAADKLQA LGKMDTTSTP GTDLIGVVTT AIATLAAAGM QPAPSTALTG VAAEVATPST
     ALGV