ID   AAAP_ANAMV              Reviewed;         320 AA.
AC   Q5SF93;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 24.
DE   RecName: Full=Appendage-associated protein;
DE   Flags: Precursor;
GN   Name=aaaP {ECO:0000312|EMBL:AAS83467.1};
OS   Anaplasma marginale (strain Virginia).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Anaplasma.
OX   NCBI_TaxID=403779;
RN   [1] {ECO:0000305, ECO:0000312|EMBL:AAS83467.1}
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=15557651; DOI=10.1128/iai.72.12.7257-7264.2004;
RA   Stich R.W., Olah G.A., Brayton K.A., Brown W.C., Fecheimer M.,
RA   Green-Church K., Jittapalapong S., Kocan K.M., McGuire T.C.,
RA   Rurangirwa F.R., Palmer G.H.;
RT   "Identification of a novel Anaplasma marginale appendage-associated protein
RT   that localizes with actin filaments during intraerythrocytic infection.";
RL   Infect. Immun. 72:7257-7264(2004).
CC   -!- FUNCTION: Associates with actin filament appendages that are formed in
CC       the inclusion appendages of the parasitophorous vacuole during
CC       infection of the host erythrocyte. {ECO:0000269|PubMed:15557651}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15557651}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY514453; AAS83467.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q5SF93; -.
DR   SMR; Q5SF93; -.
DR   GO; GO:0020003; C:symbiont-containing vacuole; IDA:UniProtKB.
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0051701; P:biological process involved in interaction with host; IDA:UniProtKB.
PE   3: Inferred from homology;
KW   Coiled coil; Secreted; Signal.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000250|UniProtKB:Q5SF96"
FT   CHAIN           29..320
FT                   /note="Appendage-associated protein"
FT                   /evidence="ECO:0000250|UniProtKB:Q5SF96"
FT                   /id="PRO_0000258018"
FT   COILED          191..251
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   320 AA;  34610 MW;  E3DC8F4073D149E7 CRC64;
     MSRGGSPGCG RRIAEELRLA EDARLRLALL GRCIVKGSPA QVRKELRAEL KAIDAEWRPV
     IARESLRKEL DAIDAEWQHA ITFWHISRAI IGSIELSKEL DAIDAEWRPV IVRESLRKEL
     KAIDAEWRPA IRLESAYRAI IGSIELSKEL KAIDAETQHA VELRRALRTI EGRIELSREL
     KAIDAEWAPR IAQAKEIAQA RESLRKELND IDAEWAPKIA QAKEIAQAKA ELAAATDALK
     RAADKLQALG KMDTTSTPGT DLIGVVTTAV TTTLAGTQPA PGTDLVGVAT PSTALGQPAP
     STALTSVAAE VATPSTALGV