ID   ATG23_CANGA             Reviewed;         440 AA.
AC   Q6FK56;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Autophagy-related protein 23;
GN   Name=ATG23; OrderedLocusNames=CAGL0M00968g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for cytoplasm to vacuole transport (Cvt) vesicle
CC       formation and efficient autophagy. Plays a role in ATG protein
CC       retrieval from the pre-autophagosomal structure (PAS) and is especially
CC       required for autophagy-dependent cycling of ATG9. Also plays a role in
CC       regulation of filamentous growth (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATG23 family. {ECO:0000305}.
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DR   EMBL; CR380959; CAG62364.1; -; Genomic_DNA.
DR   RefSeq; XP_449388.1; XM_449388.1.
DR   AlphaFoldDB; Q6FK56; -.
DR   SMR; Q6FK56; -.
DR   STRING; 5478.XP_449388.1; -.
DR   EnsemblFungi; CAG62364; CAG62364; CAGL0M00968g.
DR   GeneID; 2891157; -.
DR   KEGG; cgr:CAGL0M00968g; -.
DR   CGD; CAL0137259; CAGL0M00968g.
DR   VEuPathDB; FungiDB:CAGL0M00968g; -.
DR   eggNOG; ENOG502RZQ0; Eukaryota.
DR   HOGENOM; CLU_051067_0_0_1; -.
DR   InParanoid; Q6FK56; -.
DR   OMA; EMSEMIN; -.
DR   Proteomes; UP000002428; Chromosome M.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Autophagy; Coiled coil; Cytoplasm; Membrane; Protein transport;
KW   Reference proteome; Transport.
FT   CHAIN           1..440
FT                   /note="Autophagy-related protein 23"
FT                   /id="PRO_0000064724"
FT   COILED          32..108
FT                   /evidence="ECO:0000255"
FT   COILED          183..234
FT                   /evidence="ECO:0000255"
FT   COILED          274..311
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   440 AA;  50457 MW;  B6728C7C6E5A9381 CRC64;
     MLNDILVEVA EKTQLLESLI IPHERALTES DYSDQLENIR AEISATLNSL SNLNDLLISH
     DGPLRTEISS LMASKSKLKK INMKELTLLN EQETLETLRN DSSNLESSRP GFTTQQQQSI
     TIASSYRHEL QKYLDLVDVE KTSLNTNKLA DNSKISKEDV ENSDFNFNLK RYEKQQSILH
     SALTVNEIEI KKLETLLKEF RKDNNFIRDE LKLINSNLKS HEDLISDELK QIDESRYAIM
     QSIGYSGRNE QQSSILDSIV KLSIKKPDIR TLIQERIEEY SNLLNFIDMK LNGLDQMLQE
     YKSRKSEWAE KSILWSQCLA LISELEVTVR DQLSSAHTVG SEISPDQIKA QIKKFLTKLN
     KLLDESDLED VVYSLVRNEV NSLNVALDEM NQMPQIKNDI SDRESIHNPS FKLISKSPPK
     TGFSSENVSY KLNNTNIKKD