ID   AABP_PSEAE              Reviewed;         374 AA.
AC   Q9HUQ0;
DT   23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Amino acid binding protein {ECO:0000305};
DE   Flags: Precursor;
GN   OrderedLocusNames=PA4913 {ECO:0000312|EMBL:AAG08298.1};
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
RN   [2]
RP   FUNCTION AS A BINDING PROTEIN.
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=31627455; DOI=10.3390/ijms20205156;
RA   Fernandez M., Rico-Jimenez M., Ortega A., Daddaoua A., Garcia Garcia A.I.,
RA   Martin-Mora D., Torres N.M., Tajuelo A., Matilla M.A., Krell T.;
RT   "Determination of Ligand Profiles for Pseudomonas aeruginosa Solute Binding
RT   Proteins.";
RL   Int. J. Mol. Sci. 20:5156-5156(2019).
CC   -!- FUNCTION: Binds primarily proteinogenic amino acids.
CC       {ECO:0000269|PubMed:31627455}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the leucine-binding protein family.
CC       {ECO:0000305}.
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DR   EMBL; AE004091; AAG08298.1; -; Genomic_DNA.
DR   PIR; C83032; C83032.
DR   RefSeq; NP_253600.1; NC_002516.2.
DR   RefSeq; WP_003099985.1; NZ_QZGE01000002.1.
DR   AlphaFoldDB; Q9HUQ0; -.
DR   SMR; Q9HUQ0; -.
DR   STRING; 287.DR97_2264; -.
DR   PaxDb; Q9HUQ0; -.
DR   PRIDE; Q9HUQ0; -.
DR   EnsemblBacteria; AAG08298; AAG08298; PA4913.
DR   GeneID; 878522; -.
DR   KEGG; pae:PA4913; -.
DR   PATRIC; fig|208964.12.peg.5146; -.
DR   PseudoCAP; PA4913; -.
DR   HOGENOM; CLU_027128_6_0_6; -.
DR   InParanoid; Q9HUQ0; -.
DR   OMA; GAQYWKG; -.
DR   PhylomeDB; Q9HUQ0; -.
DR   BioCyc; PAER208964:G1FZ6-5027-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   InterPro; IPR028081; Leu-bd.
DR   InterPro; IPR000709; Leu_Ile_Val-bd.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   Pfam; PF13458; Peripla_BP_6; 1.
DR   PRINTS; PR00337; LEUILEVALBP.
DR   SUPFAM; SSF53822; SSF53822; 1.
PE   1: Evidence at protein level;
KW   Amino-acid transport; Periplasm; Reference proteome; Signal; Transport.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..374
FT                   /note="Amino acid binding protein"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_5004326797"
SQ   SEQUENCE   374 AA;  39798 MW;  5E2698DAD130DFCD CRC64;
     MSKKLFRKGI LALAVSSVMG LSTHALADVV IGVAGPHTGA NASFGEQYWR GASQAAEDIN
     AAGGINGEKI KLVKADDACE PKQAVAVANR LVDQDKAIAV VGHFCSSSTI PASEVYDEAG
     IIAITPGSTN PQVTERGLSG MFRMCGRDDQ QGVVAGDYIV NVLKAKKVAV IHDKDTYGQG
     LADATRAQLN KLGVKEVLYE GLTRGEKDFN ALVTKIRASG AEVVYFGGLH PEAGPLVRQM
     REQGLTARFM SDDGVVTDEL ATTAGGPQYV KGVLMTFGAD PRLIPDGKAV VEKFRAGGFE
     PEGYTLYSYA SIQSLAAAFN GAGANDPAKA AEWLKSHPVQ TVMGKKEWDK KGDLKVSDYV
     VYEWDDKGKY HQLP