ID   PROF_CWPXB              Reviewed;         133 AA.
AC   Q77DS0;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   29-SEP-2021, entry version 49.
DE   RecName: Full=Profilin;
GN   OrderedLocusNames=CPXV179;
OS   Cowpox virus (strain Brighton Red) (CPV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=265872;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=9685; Felis catus (Cat) (Felis silvestris catus).
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=9785; Loxodonta africana (African elephant).
OH   NCBI_TaxID=29092; Microtus agrestis (Short-tailed field vole).
OH   NCBI_TaxID=10090; Mus musculus (Mouse).
OH   NCBI_TaxID=447135; Myodes glareolus (Bank vole) (Clethrionomys glareolus).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Dietrich F.S., Ray C.A., Sharma A.D., Allen A., Pickup D.J.;
RL   Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: More likely to influence phosphoinositide metabolism than
CC       actin assembly. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the profilin family. {ECO:0000305}.
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DR   EMBL; AF482758; AAM13619.1; -; Genomic_DNA.
DR   RefSeq; NP_619961.1; NC_003663.2.
DR   SMR; Q77DS0; -.
DR   GeneID; 1486058; -.
DR   KEGG; vg:1486058; -.
DR   Proteomes; UP000152733; Genome.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   InterPro; IPR005455; PFN.
DR   InterPro; IPR036140; PFN_sf.
DR   InterPro; IPR027310; Profilin_CS.
DR   Pfam; PF00235; Profilin; 1.
DR   SMART; SM00392; PROF; 1.
DR   SUPFAM; SSF55770; SSF55770; 1.
DR   PROSITE; PS00414; PROFILIN; 1.
PE   3: Inferred from homology;
KW   Actin-binding.
FT   CHAIN           1..133
FT                   /note="Profilin"
FT                   /id="PRO_0000199687"
SQ   SEQUENCE   133 AA;  15052 MW;  C76E5D9FA31E8669 CRC64;
     MAEWHKIIED ISKNNKFEDA AIVDYKTTKN VLAAIPNRTF AKINPGEIIP LITNRNILKP
     LIGQKYCIVY TNSLMDENTY AMELLTGYAP VSPIVIARTH TALIFLMGKP TTSRRDVYRT
     CRDHATRVRA TGN