ID   PROF_CWPXG              Reviewed;         133 AA.
AC   Q80DT4;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   12-AUG-2020, entry version 39.
DE   RecName: Full=Profilin;
GN   ORFNames=A44R;
OS   Cowpox virus (strain GRI-90 / Grishak) (CPV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=265871;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=9685; Felis catus (Cat) (Felis silvestris catus).
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=9785; Loxodonta africana (African elephant).
OH   NCBI_TaxID=29092; Microtus agrestis (Short-tailed field vole).
OH   NCBI_TaxID=10090; Mus musculus (Mouse).
OH   NCBI_TaxID=447135; Myodes glareolus (Bank vole) (Clethrionomys glareolus).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Shchelkunov S.N., Safronov P.F., Totmenin A.V., Miheev M.V.,
RA   Ryazankina O.I., Petrov N.A., Gutorov V.V., Kotwal G.J., Sandakhchiev L.S.;
RT   "Structure-function and organization of cowpox virus strain GRI-90 complete
RT   genome.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: More likely to influence phosphoinositide metabolism than
CC       actin assembly. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the profilin family. {ECO:0000305}.
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DR   EMBL; X94355; CAD90711.1; -; Genomic_DNA.
DR   SMR; Q80DT4; -.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   InterPro; IPR005455; PFN.
DR   InterPro; IPR036140; PFN_sf.
DR   InterPro; IPR027310; Profilin_CS.
DR   Pfam; PF00235; Profilin; 1.
DR   SMART; SM00392; PROF; 1.
DR   SUPFAM; SSF55770; SSF55770; 1.
DR   PROSITE; PS00414; PROFILIN; 1.
PE   3: Inferred from homology;
KW   Actin-binding.
FT   CHAIN           1..133
FT                   /note="Profilin"
FT                   /id="PRO_0000199688"
SQ   SEQUENCE   133 AA;  15003 MW;  2FF189D84198F2B9 CRC64;
     MAEWHKIIED ISKNNKFEDA AIVDYKTTKN VLAAIPNRTF AKINPGEVIP LITNHNILKP
     LIGQKFCIVY TNSLMDENTY AMELLTGYAP VSPIVIARTH TALIFLMGKP TTSRRDVYRT
     CRDHATRVRA TGN