ID   PROF_THOAA              Reviewed;         128 AA.
AC   A0A1Q9PA05;
DT   12-AUG-2020, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2017, sequence version 1.
DT   25-MAY-2022, entry version 12.
DE   RecName: Full=Thor profilin {ECO:0000303|PubMed:30283132};
GN   ORFNames=ThorAB25_04690;
OS   Thorarchaeota archaeon (strain AB_25).
OC   Archaea; Asgard group; Candidatus Thorarchaeota.
OX   NCBI_TaxID=1837170;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AB_25;
RX   PubMed=28077874; DOI=10.1038/nature21031;
RA   Zaremba-Niedzwiedzka K., Caceres E.F., Saw J.H., Backstrom D.,
RA   Juzokaite L., Vancaester E., Seitz K.W., Anantharaman K., Starnawski P.,
RA   Kjeldsen K.U., Scott M.B., Nunoura T., Banfield J.F., Schramm A.,
RA   Baker B.J., Spang A., Ettema T.J.G.;
RT   "Asgard archaea illuminate the origin of eukaryotic cellular complexity.";
RL   Nature 541:353-358(2017).
RN   [2]
RP   POSSIBLE LACK OF FUNCTION AS A PROFILIN.
RX   PubMed=30283132; DOI=10.1038/s41586-018-0548-6;
RA   Akil C., Robinson R.C.;
RT   "Genomes of Asgard archaea encode profilins that regulate actin.";
RL   Nature 562:439-443(2018).
CC   -!- FUNCTION: Has no profilin activity against rabbit actin.
CC       {ECO:0000269|PubMed:30283132}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000305|PubMed:30283132}.
CC   -!- SIMILARITY: Belongs to the Asgard profilin family. {ECO:0000305}.
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DR   EMBL; MEHG01000010; OLS31208.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1Q9PA05; -.
DR   SMR; A0A1Q9PA05; -.
DR   EnsemblBacteria; OLS31208; OLS31208; ThorAB25_04690.
DR   Proteomes; UP000185561; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   InterPro; IPR005455; PFN.
DR   InterPro; IPR036140; PFN_sf.
DR   Pfam; PF00235; Profilin; 1.
DR   SUPFAM; SSF55770; SSF55770; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Cytoskeleton.
FT   CHAIN           1..128
FT                   /note="Thor profilin"
FT                   /id="PRO_0000450554"
SQ   SEQUENCE   128 AA;  13892 MW;  779208C0D00E1413 CRC64;
     MSDPVMDAYT QAYNSSGNMV QAFGVISESG QVLWQSNNWD LTADASTLMS AVKSRASSVI
     QNQVKYSTMR STPESLVARN VQGSGILILT KIDTTSDRWV VAWADAQAQP DGVYVDVDRA
     AKTLRGKI