ID   ATG29_PENRW             Reviewed;         412 AA.
AC   A7KAN7;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   03-AUG-2022, entry version 43.
DE   RecName: Full=Autophagy-related protein 29;
GN   Name=atg29; ORFNames=Pc20g02170;
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS   54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RX   PubMed=17204848; DOI=10.4161/auto.3595;
RA   Meijer W.H., van der Klei I.J., Veenhuis M., Kiel J.A.K.W.;
RT   "ATG genes involved in non-selective autophagy are conserved from yeast to
RT   man, but the selective Cvt and pexophagy pathways also require organism-
RT   specific genes.";
RL   Autophagy 3:106-116(2007).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255;
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA   van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA   Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- FUNCTION: Plays a role in autophagy. Functions at the preautophagosomal
CC       structure (PAS) in order to form normal autophagosomes under starvation
CC       conditions. Also plays a role in mitophagy and regulation of
CC       filamentous growth (By similarity). {ECO:0000250,
CC       ECO:0000269|PubMed:17204848}.
CC   -!- SUBCELLULAR LOCATION: Preautophagosomal structure {ECO:0000250}.
CC       Note=Localizes also to other perivacuolar punctate structures.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATG29 family. {ECO:0000305}.
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DR   EMBL; EF110903; ABO31324.1; -; Genomic_DNA.
DR   EMBL; AM920435; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A7KAN7; -.
DR   VEuPathDB; FungiDB:PCH_Pc20g02170; -.
DR   Proteomes; UP000000724; Contig Pc00c20.
DR   GO; GO:0000407; C:phagophore assembly site; IEA:UniProtKB-SubCell.
DR   GO; GO:0000045; P:autophagosome assembly; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.2570; -; 1.
DR   InterPro; IPR039113; ATG29.
DR   InterPro; IPR040666; Atg29_N.
DR   InterPro; IPR039362; ATG29_sf.
DR   PANTHER; PTHR40012; PTHR40012; 1.
DR   Pfam; PF18388; ATG29_N; 1.
PE   3: Inferred from homology;
KW   Autophagy; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..412
FT                   /note="Autophagy-related protein 29"
FT                   /id="PRO_0000318059"
FT   REGION          92..379
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..138
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        145..168
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        169..188
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        257..278
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        305..379
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   412 AA;  45151 MW;  A1F3AA1014A7BEDB CRC64;
     MSIKVDPVDT NFTVFIRLPF PRGDFVDPPP VEWNASKDQA LWDILSRPSK GDIDWKALAE
     NFDVTLQFLL QQAAWLYDRQ LSQVRAQMRK VNTTQSTSPS PALGSVSGSA ALSGQPQRET
     LATGSRAPSR QVSQQKDIPL RAPENRRTSF TSTTATNLTP GSRDPTRTGT PTIEDKEPRW
     DSFGRRPSAV RREQPPVASL PRSPPLEEEP LSSSSPEESG SDEEDTTRRA PLFKRFGKFS
     TQRSGLRDDE DNEEDTPAFL PLAREHEHTH HERPVQELST TLRLDAERAA AQRRHPEQRA
     GPRAPVPTDS STSSMSSGGR SSLPDGARPT SQGAPVLSPQ SAAERQNSRK STASGREASD
     GTPSMGSSFS DLDDASVTQS ALEEALLSNM QHGGMASRMS TISHALRSRY LQ