PROQ_ECOK1
ID PROQ_ECOK1 Reviewed; 232 AA.
AC A1ABZ7;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=RNA chaperone ProQ {ECO:0000255|HAMAP-Rule:MF_00749};
GN Name=proQ {ECO:0000255|HAMAP-Rule:MF_00749}; OrderedLocusNames=Ecok1_16930;
GN ORFNames=APECO1_886;
OS Escherichia coli O1:K1 / APEC.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=405955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17293413; DOI=10.1128/jb.01726-06;
RA Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J.,
RA Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K.;
RT "The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7
RT shares strong similarities with human extraintestinal pathogenic E. coli
RT genomes.";
RL J. Bacteriol. 189:3228-3236(2007).
CC -!- FUNCTION: RNA chaperone with significant RNA binding, RNA strand
CC exchange and RNA duplexing activities. May regulate ProP activity
CC through an RNA-based, post-transcriptional mechanism.
CC {ECO:0000255|HAMAP-Rule:MF_00749}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00749}.
CC -!- SIMILARITY: Belongs to the ProQ family. {ECO:0000255|HAMAP-
CC Rule:MF_00749}.
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DR EMBL; CP000468; ABJ01187.1; -; Genomic_DNA.
DR RefSeq; WP_000431376.1; NC_008563.1.
DR AlphaFoldDB; A1ABZ7; -.
DR SMR; A1ABZ7; -.
DR EnsemblBacteria; ABJ01187; ABJ01187; APECO1_886.
DR KEGG; ecv:APECO1_886; -.
DR HOGENOM; CLU_113254_0_0_6; -.
DR OMA; WRYLKGV; -.
DR Proteomes; UP000008216; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0033592; F:RNA strand annealing activity; IEA:UniProtKB-UniRule.
DR GO; GO:0034057; F:RNA strand-exchange activity; IEA:UniProtKB-UniRule.
DR GO; GO:0010608; P:post-transcriptional regulation of gene expression; IEA:InterPro.
DR Gene3D; 1.10.1710.10; -; 1.
DR HAMAP; MF_00749; ProQ; 1.
DR InterPro; IPR023529; ProQ.
DR InterPro; IPR016103; ProQ/FinO.
DR InterPro; IPR036442; ProQ/FinO_sf.
DR InterPro; IPR035236; ProQ_C.
DR PANTHER; PTHR38106; PTHR38106; 1.
DR Pfam; PF04352; ProQ; 1.
DR Pfam; PF17516; ProQ_C; 1.
DR SMART; SM00945; ProQ; 1.
DR SUPFAM; SSF48657; SSF48657; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; RNA-binding.
FT CHAIN 1..232
FT /note="RNA chaperone ProQ"
FT /id="PRO_0000303088"
FT REGION 105..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..177
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 232 AA; 25878 MW; 1E8AED6F9FB50BF2 CRC64;
MENQPKLNSS KEVIAFLAER FPHCFSAEGE ARPLKIGIFQ DLVDRVAGEM NLSKTQLRSA
LRLYTSSWRY LYGVKPGATR VDLDGNPCGE LDEQHVEHAR KQLEEAKARV QAQRAEQQAK
KREAAAAAGE KEDAPRRERK PRPTTPRRKE GAERKPRSQK PVEKAPKTVK APREEQHTPV
SDISALTVGQ ALKVKAGQNA MDATVLEITK DGVRVQLNSG MSLIVRAEHL VF