PROQ_ECOSE
ID PROQ_ECOSE Reviewed; 232 AA.
AC B6IBQ9;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-DEC-2008, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=RNA chaperone ProQ {ECO:0000255|HAMAP-Rule:MF_00749};
GN Name=proQ {ECO:0000255|HAMAP-Rule:MF_00749}; OrderedLocusNames=ECSE_2006;
OS Escherichia coli (strain SE11).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=409438;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SE11;
RX PubMed=18931093; DOI=10.1093/dnares/dsn026;
RA Oshima K., Toh H., Ogura Y., Sasamoto H., Morita H., Park S.-H., Ooka T.,
RA Iyoda S., Taylor T.D., Hayashi T., Itoh K., Hattori M.;
RT "Complete genome sequence and comparative analysis of the wild-type
RT commensal Escherichia coli strain SE11 isolated from a healthy adult.";
RL DNA Res. 15:375-386(2008).
CC -!- FUNCTION: RNA chaperone with significant RNA binding, RNA strand
CC exchange and RNA duplexing activities. May regulate ProP activity
CC through an RNA-based, post-transcriptional mechanism.
CC {ECO:0000255|HAMAP-Rule:MF_00749}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00749}.
CC -!- SIMILARITY: Belongs to the ProQ family. {ECO:0000255|HAMAP-
CC Rule:MF_00749}.
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DR EMBL; AP009240; BAG77530.1; -; Genomic_DNA.
DR RefSeq; WP_000431370.1; NC_011415.1.
DR AlphaFoldDB; B6IBQ9; -.
DR SMR; B6IBQ9; -.
DR EnsemblBacteria; BAG77530; BAG77530; ECSE_2006.
DR GeneID; 66674279; -.
DR KEGG; ecy:ECSE_2006; -.
DR HOGENOM; CLU_113254_0_0_6; -.
DR OMA; WRYLKGV; -.
DR Proteomes; UP000008199; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0033592; F:RNA strand annealing activity; IEA:UniProtKB-UniRule.
DR GO; GO:0034057; F:RNA strand-exchange activity; IEA:UniProtKB-UniRule.
DR GO; GO:0010608; P:post-transcriptional regulation of gene expression; IEA:InterPro.
DR Gene3D; 1.10.1710.10; -; 1.
DR HAMAP; MF_00749; ProQ; 1.
DR InterPro; IPR023529; ProQ.
DR InterPro; IPR016103; ProQ/FinO.
DR InterPro; IPR036442; ProQ/FinO_sf.
DR InterPro; IPR035236; ProQ_C.
DR PANTHER; PTHR38106; PTHR38106; 1.
DR Pfam; PF04352; ProQ; 1.
DR Pfam; PF17516; ProQ_C; 1.
DR SMART; SM00945; ProQ; 1.
DR SUPFAM; SSF48657; SSF48657; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; RNA-binding.
FT CHAIN 1..232
FT /note="RNA chaperone ProQ"
FT /id="PRO_1000133295"
FT REGION 105..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..177
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 232 AA; 25862 MW; 1E8AFBA345A3C728 CRC64;
MENQPKLNSS KEVIAFLAER FPHCFSAEGE ARPLKIGIFQ DLVDRVAGEM NLSKTQLRSA
LRLYTSSWRY LYGVKPGATR VDLDGNPCGE LDEQHVEHAR KQLEEAKARV QAQRAEQQAK
KREAAAAAGE KEDAPRRERK PRPTTPRRKE GAERKPRAQK PVEKAPKTVK APREEQHTPV
SDISALTVGQ ALKVKAGQNA MDATVLEITK DGVRVQLNSG MSLIVRAEHL VF