PROQ_HAEIN
ID PROQ_HAEIN Reviewed; 197 AA.
AC P44286; O05079; Q57119;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 02-FEB-2004, sequence version 3.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=RNA chaperone ProQ {ECO:0000255|HAMAP-Rule:MF_00749};
GN Name=proQ {ECO:0000255|HAMAP-Rule:MF_00749};
GN OrderedLocusNames=HI_1669/HI_1670;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- FUNCTION: RNA chaperone with significant RNA binding, RNA strand
CC exchange and RNA duplexing activities. {ECO:0000255|HAMAP-
CC Rule:MF_00749}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00749}.
CC -!- SIMILARITY: Belongs to the ProQ family. {ECO:0000255|HAMAP-
CC Rule:MF_00749}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC23315.1; Type=Frameshift; Note=Produces two separate ORFs.; Evidence={ECO:0000305};
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DR EMBL; L42023; AAC23323.1; ALT_FRAME; Genomic_DNA.
DR EMBL; L42023; AAC23315.1; ALT_FRAME; Genomic_DNA.
DR PIR; G64135; G64135.
DR PIR; H64039; H64039.
DR RefSeq; NP_439812.1; NC_000907.1.
DR AlphaFoldDB; P44286; -.
DR SMR; P44286; -.
DR STRING; 71421.HI_1669; -.
DR EnsemblBacteria; AAC23315; AAC23315; HI_1669.
DR EnsemblBacteria; AAC23323; AAC23323; HI_1670.
DR KEGG; hin:HI_1669; -.
DR KEGG; hin:HI_1670; -.
DR PATRIC; fig|71421.8.peg.1748; -.
DR eggNOG; COG3109; Bacteria.
DR HOGENOM; CLU_3270840_0_0_6; -.
DR PhylomeDB; P44286; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0033592; F:RNA strand annealing activity; IBA:GO_Central.
DR GO; GO:0034057; F:RNA strand-exchange activity; IBA:GO_Central.
DR GO; GO:0010608; P:post-transcriptional regulation of gene expression; IBA:GO_Central.
DR Gene3D; 1.10.1710.10; -; 1.
DR HAMAP; MF_00749; ProQ; 1.
DR InterPro; IPR023529; ProQ.
DR InterPro; IPR016103; ProQ/FinO.
DR InterPro; IPR036442; ProQ/FinO_sf.
DR InterPro; IPR035236; ProQ_C.
DR PANTHER; PTHR38106; PTHR38106; 1.
DR Pfam; PF04352; ProQ; 1.
DR Pfam; PF17516; ProQ_C; 1.
DR SMART; SM00945; ProQ; 1.
DR SUPFAM; SSF48657; SSF48657; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Reference proteome; RNA-binding.
FT CHAIN 1..197
FT /note="RNA chaperone ProQ"
FT /id="PRO_0000214618"
FT REGION 115..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..133
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 197 AA; 21729 MW; 4B8DE7A74130B36C CRC64;
MQTEVQKLTN AKAIITYLAE KFPLCFVLEG EAKPLKIGLF QDLAEALQDD ERVSKTQLRQ
ALRQYTSNWR YLYGCREGAV RVDLQGNPAG VLDAEHVAHA AQQLAEAKAR FAEKRAAAKK
AQQKKHPRKP ANKNLKKESK LSLSAVDFSQ ISVGSVVKVK AGDNAKKATV VEVLKDSARV
ELENGLIMNV AADRLFA
