PROQ_SALDC
ID PROQ_SALDC Reviewed; 228 AA.
AC B5FTI8;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 14-OCT-2008, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=RNA chaperone ProQ {ECO:0000255|HAMAP-Rule:MF_00749};
GN Name=proQ {ECO:0000255|HAMAP-Rule:MF_00749}; OrderedLocusNames=SeD_A1469;
OS Salmonella dublin (strain CT_02021853).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=439851;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT_02021853;
RX PubMed=21602358; DOI=10.1128/jb.00297-11;
RA Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA Leclerc J.E., Ravel J., Cebula T.A.;
RT "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT CRISPR-mediated adaptive sublineage evolution.";
RL J. Bacteriol. 193:3556-3568(2011).
CC -!- FUNCTION: RNA chaperone with significant RNA binding, RNA strand
CC exchange and RNA duplexing activities. May regulate ProP activity
CC through an RNA-based, post-transcriptional mechanism.
CC {ECO:0000255|HAMAP-Rule:MF_00749}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00749}.
CC -!- SIMILARITY: Belongs to the ProQ family. {ECO:0000255|HAMAP-
CC Rule:MF_00749}.
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DR EMBL; CP001144; ACH74582.1; -; Genomic_DNA.
DR RefSeq; WP_000431401.1; NC_011205.1.
DR AlphaFoldDB; B5FTI8; -.
DR SMR; B5FTI8; -.
DR KEGG; sed:SeD_A1469; -.
DR HOGENOM; CLU_113254_0_0_6; -.
DR OMA; WRYLKGV; -.
DR Proteomes; UP000008322; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0033592; F:RNA strand annealing activity; IEA:UniProtKB-UniRule.
DR GO; GO:0034057; F:RNA strand-exchange activity; IEA:UniProtKB-UniRule.
DR GO; GO:0010608; P:post-transcriptional regulation of gene expression; IEA:InterPro.
DR Gene3D; 1.10.1710.10; -; 1.
DR HAMAP; MF_00749; ProQ; 1.
DR InterPro; IPR023529; ProQ.
DR InterPro; IPR016103; ProQ/FinO.
DR InterPro; IPR036442; ProQ/FinO_sf.
DR InterPro; IPR035236; ProQ_C.
DR PANTHER; PTHR38106; PTHR38106; 1.
DR Pfam; PF04352; ProQ; 1.
DR Pfam; PF17516; ProQ_C; 1.
DR SMART; SM00945; ProQ; 1.
DR SUPFAM; SSF48657; SSF48657; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; RNA-binding.
FT CHAIN 1..228
FT /note="RNA chaperone ProQ"
FT /id="PRO_1000133302"
FT REGION 107..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..176
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 228 AA; 25438 MW; F2CEBA1B8B83F8C8 CRC64;
MENQPKLNSS KEVIAFLAER FPHCFSAEGE ARPLKIGIFQ DLVERVGGEM NLSKTQLRSA
LRLYTSSWRY LYGVKPGATR VDLDGNPCGE LEEQHVEHAR KQLEEAKARV QAQRAEQQAK
KREAAAAAGE KEDAPRRERK PRPVARRKEG AERKPRADKP TTKAPRAPRE EKHTPVSDIS
VLTVGQSLKV KAGNNAMDAT VLEITKDGVR VQLNSGMSLI VRAEHLVF