ID   PRP45_USTMA             Reviewed;         621 AA.
AC   Q4PB95; A0A0D1DZ00;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-SEP-2015, sequence version 2.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Pre-mRNA-processing protein 45;
GN   Name=PRP45; ORFNames=UMAG_02618;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA   Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA   Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA   Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA   Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA   Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA   Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA   Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA   Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA   Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA   Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT   maydis.";
RL   Nature 444:97-101(2006).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021;
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SNW family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM003145; KIS69274.1; -; Genomic_DNA.
DR   RefSeq; XP_011389016.1; XM_011390714.1.
DR   AlphaFoldDB; Q4PB95; -.
DR   SMR; Q4PB95; -.
DR   STRING; 5270.UM02618P0; -.
DR   EnsemblFungi; KIS69274; KIS69274; UMAG_02618.
DR   GeneID; 23563326; -.
DR   KEGG; uma:UMAG_02618; -.
DR   VEuPathDB; FungiDB:UMAG_02618; -.
DR   eggNOG; KOG2441; Eukaryota.
DR   HOGENOM; CLU_006601_2_0_1; -.
DR   InParanoid; Q4PB95; -.
DR   OrthoDB; 1455730at2759; -.
DR   Proteomes; UP000000561; Chromosome 6.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR   InterPro; IPR017862; SKI-int_prot_SKIP.
DR   InterPro; IPR004015; SKI-int_prot_SKIP_SNW-dom.
DR   PANTHER; PTHR12096; PTHR12096; 1.
DR   Pfam; PF02731; SKIP_SNW; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome.
FT   CHAIN           1..621
FT                   /note="Pre-mRNA-processing protein 45"
FT                   /id="PRO_0000084823"
FT   REGION          1..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          137..164
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          220..251
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          347..438
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          542..621
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        32..55
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        368..382
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        414..438
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        595..621
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   621 AA;  68483 MW;  781C5C9E43A9B609 CRC64;
     MSATLQSFLP APKYSALPHS RDDDENDEYD NTEAGPSTSS SSSALVSTSS PSIPPYGQRA
     AWRPRTQADY ANGGAYPECH VAQYPLDMGR NRSAATSNKL AMRIDGEGNK RYDAIVKQSL
     RPGQTVQTEF KDLVPLSQRT DIKEKDRNSG FERPSHEEVM SNTERTRLAL EAITKGKNKP
     VVPKAGNLPG QQQAAQFIRY TPAQQGAGNG TQRIIKMTEA QRDPLEPPRH RFKKTAAGPP
     SPPPPVLRSP PRKVTAQEQK DWMIPPAVSN WKNNKGYTIP LDKRLAADAS GIQDVVINDN
     FAQFAEALHL ADRHAREEVR QRSIMQQKLA AKEKAAKEEH LRNLAQRARE ERAGVSSATP
     SVLGRDDDVA SRLADSDARP TRATPRAEGG MSAMLAGYRS DSDSDESAAS DEEDDEGARE
     RDRIREERRR ERQRELRMSN MGIEQRTKQL LREQNRDISE KVALGLAKPT ASKESMTDSR
     LFNQGESLAA GYGDEDSYNL YDKPLFSGSS AAAAIYRRPA ARGGANDIYS GADDTALEEE
     LGKNDRFGLG QSKFRGVQGD ADRDSGSGSA PVRSGPVQFE KDTSDPFAIN QFLEDAKRGI
     KRTSDQDADD ARKKLRDEHD S