ID   PRP_CALVI               Reviewed;          22 AA.
AC   C0HJY0;
DT   17-FEB-2016, integrated into UniProtKB/Swiss-Prot.
DT   17-FEB-2016, sequence version 1.
DT   25-MAY-2022, entry version 6.
DE   RecName: Full=Proline-rich peptide {ECO:0000303|PubMed:26177023};
DE   Flags: Fragment;
OS   Calliphora vicina (Blue blowfly) (Calliphora erythrocephala).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC   Calliphoridae; Calliphorinae; Calliphora.
OX   NCBI_TaxID=7373 {ECO:0000303|PubMed:26177023};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE.
RC   TISSUE=Hemolymph {ECO:0000303|Ref.1};
RA   Chernysh S., Gordja N.A., Simnonenko N.P.;
RT   "Dia pause and immune response: induction of antimicrobial peptides
RT   synthesis in the blowfly, Calliphora vicina R.-D. (Diptera:
RT   Calliphoridae).";
RL   Entomol. Sci. 3:139-144(2000).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, INDUCTION, AND MASS SPECTROMETRY.
RC   TISSUE=Hemolymph {ECO:0000303|PubMed:26177023};
RX   PubMed=26177023; DOI=10.1371/journal.pone.0130788;
RA   Chernysh S., Gordya N., Suborova T.;
RT   "Insect antimicrobial peptide complexes prevent resistance development in
RT   bacteria.";
RL   PLoS ONE 10:E0130788-E0130788(2015).
CC   -!- FUNCTION: Antibacterial peptide active against Gram-positive bacterium
CC       M.luteus and Gram-negative bacterium E.coli.
CC       {ECO:0000269|PubMed:26177023}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:26177023}.
CC   -!- INDUCTION: By bacterial infection. {ECO:0000269|PubMed:26177023}.
CC   -!- MASS SPECTROMETRY: Mass=2987; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:26177023};
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DR   AlphaFoldDB; C0HJY0; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Direct protein sequencing; Immunity;
KW   Innate immunity; Secreted.
FT   CHAIN           1..>22
FT                   /note="Proline-rich peptide"
FT                   /id="PRO_0000435611"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         22
FT                   /evidence="ECO:0000303|PubMed:26177023"
SQ   SEQUENCE   22 AA;  2505 MW;  1172C616DEDD9839 CRC64;
     FVDRNRIPRS NNGPKIPIIS NP