ID   PRR13_RAT               Reviewed;         139 AA.
AC   Q5U1W2;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Proline-rich protein 13;
GN   Name=Prr13;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Negatively regulates TSP1 expression at the level of
CC       transcription. This down-regulation was shown to reduce taxane-induced
CC       apoptosis (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; BC086446; AAH86446.1; -; mRNA.
DR   RefSeq; NP_001008380.1; NM_001008379.1.
DR   AlphaFoldDB; Q5U1W2; -.
DR   STRING; 10116.ENSRNOP00000048789; -.
DR   PaxDb; Q5U1W2; -.
DR   Ensembl; ENSRNOT00000113574; ENSRNOP00000091219; ENSRNOG00000042094.
DR   GeneID; 363004; -.
DR   KEGG; rno:363004; -.
DR   UCSC; RGD:1307129; rat.
DR   CTD; 54458; -.
DR   RGD; 1307129; Prr13.
DR   eggNOG; ENOG502R4RR; Eukaryota.
DR   GeneTree; ENSGT00730000113467; -.
DR   HOGENOM; CLU_140437_0_0_1; -.
DR   InParanoid; Q5U1W2; -.
DR   OMA; VNPACPP; -.
DR   OrthoDB; 1640659at2759; -.
DR   PRO; PR:Q5U1W2; -.
DR   Proteomes; UP000002494; Chromosome 7.
DR   Bgee; ENSRNOG00000042094; Expressed in duodenum and 20 other tissues.
DR   ExpressionAtlas; Q5U1W2; baseline and differential.
DR   Genevisible; Q5U1W2; RN.
DR   GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..139
FT                   /note="Proline-rich protein 13"
FT                   /id="PRO_0000243948"
FT   REGION          1..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..92
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        103..125
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   139 AA;  14334 MW;  CAF374B773BFB281 CRC64;
     MWNPSAGPNP YPPQVVCPGG SNPACPPSQN PAFPPGPCPP GIPQGNPAFP PCRPPYPVPQ
     PGCPGYQPSG PYPPPYPPAA PGMCPVNPPA PGMVGPGIVI DKKTRKKMKK AHKKSHKHHK
     HGKHSSSSSS SSSSSSDSD