PRR19_BOVIN
ID PRR19_BOVIN Reviewed; 363 AA.
AC Q0P5M0;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 19-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 66.
DE RecName: Full=Proline-rich protein 19 {ECO:0000250|UniProtKB:A6NJB7};
GN Name=PRR19 {ECO:0000250|UniProtKB:A6NJB7};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Thalamus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Promotes meiotic crossing over formation through its
CC interaction with CNTD1 by participating in the crossover
CC differentiation step of crossover-specific recombination intermediates.
CC {ECO:0000250|UniProtKB:B2RW88}.
CC -!- SUBUNIT: Interacts with CNTD1. {ECO:0000250|UniProtKB:B2RW88}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:B2RW88}.
CC Chromosome {ECO:0000250|UniProtKB:B2RW88}. Note=Co-localized at
CC crossover sites with CNTD1. Localizes on synapsed chromosome only in
CC mid/late pachytene spermatocytes. {ECO:0000250|UniProtKB:B2RW88}.
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DR EMBL; BC119867; AAI19868.1; -; mRNA.
DR RefSeq; NP_001069103.1; NM_001075635.1.
DR RefSeq; XP_005219308.1; XM_005219251.3.
DR RefSeq; XP_010813337.1; XM_010815035.2.
DR RefSeq; XP_010813338.1; XM_010815036.2.
DR RefSeq; XP_010813339.1; XM_010815037.2.
DR RefSeq; XP_010813340.1; XM_010815038.2.
DR RefSeq; XP_015313644.1; XM_015458158.1.
DR AlphaFoldDB; Q0P5M0; -.
DR STRING; 9913.ENSBTAP00000041430; -.
DR PaxDb; Q0P5M0; -.
DR Ensembl; ENSBTAT00000017664; ENSBTAP00000041430; ENSBTAG00000013283.
DR GeneID; 513695; -.
DR KEGG; bta:513695; -.
DR CTD; 284338; -.
DR VEuPathDB; HostDB:ENSBTAG00000013283; -.
DR VGNC; VGNC:33395; PRR19.
DR eggNOG; ENOG502T05H; Eukaryota.
DR GeneTree; ENSGT00390000010703; -.
DR HOGENOM; CLU_073234_0_0_1; -.
DR InParanoid; Q0P5M0; -.
DR OMA; PFQRPEK; -.
DR OrthoDB; 1194731at2759; -.
DR TreeFam; TF341908; -.
DR Proteomes; UP000009136; Chromosome 18.
DR Bgee; ENSBTAG00000013283; Expressed in pons and 96 other tissues.
DR GO; GO:0005694; C:chromosome; ISS:UniProtKB.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR InterPro; IPR029355; Pro-rich_19.
DR PANTHER; PTHR37346; PTHR37346; 1.
DR Pfam; PF15455; Pro-rich_19; 1.
PE 2: Evidence at transcript level;
KW Chromosome; Meiosis; Nucleus; Reference proteome.
FT CHAIN 1..363
FT /note="Proline-rich protein 19"
FT /id="PRO_0000332272"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 104..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 245..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 308..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..260
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..324
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 363 AA; 39305 MW; 443BC75575EA76D8 CRC64;
MDPGEPAPKP FQQPEKPGRV RRRKTRRERN EALAGSRQPL TYQHPPVASR DPHMVLRNSV
APTAAKLVVI TQGRLSRDHR GLFNHEVKSL DVARLLSSES LELGTPALTT KSSPSPGRGQ
QPSLQSRGKE NQVPGGSGPG PPSPPQLPDL EQLLGELQCQ LILPRAFPRR NLVQEARDAI
VGTLQACHGC VPDLTLVLRG CQPHLPGTDP GALKRQRMTP SWINSPEQAP GEGRQRRRQG
TKELTFAVPP TSSTPTVHQV SLAPPKGPWP PPLSSLPSPS GAAWGPPTAF DLLKSIWLVA
TPPPPRPWGI GPPQLLPQPP SPLLPRSSAL DWSPSPPAPL PSLSWMVAQS SPEAWSFPPM
RLY
