PRR30_MOUSE
ID PRR30_MOUSE Reviewed; 401 AA.
AC Q9D9B7; E9QQ59;
DT 04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 2.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Proline-rich protein 30;
GN Name=Prr30;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
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DR EMBL; AK007164; BAB24878.1; -; mRNA.
DR EMBL; CT010516; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS36999.1; -.
DR RefSeq; NP_083956.1; NM_029680.1.
DR RefSeq; XP_006519738.1; XM_006519675.1.
DR AlphaFoldDB; Q9D9B7; -.
DR STRING; 10090.ENSMUSP00000060206; -.
DR iPTMnet; Q9D9B7; -.
DR PhosphoSitePlus; Q9D9B7; -.
DR PaxDb; Q9D9B7; -.
DR PRIDE; Q9D9B7; -.
DR ProteomicsDB; 291746; -.
DR Antibodypedia; 55555; 56 antibodies from 15 providers.
DR Ensembl; ENSMUST00000057718; ENSMUSP00000060206; ENSMUSG00000042888.
DR Ensembl; ENSMUST00000187304; ENSMUSP00000139590; ENSMUSG00000042888.
DR GeneID; 76627; -.
DR KEGG; mmu:76627; -.
DR UCSC; uc007uvk.1; mouse.
DR CTD; 339779; -.
DR MGI; MGI:1923877; Prr30.
DR VEuPathDB; HostDB:ENSMUSG00000042888; -.
DR eggNOG; ENOG502SSVJ; Eukaryota.
DR GeneTree; ENSGT00390000005754; -.
DR HOGENOM; CLU_056385_0_0_1; -.
DR InParanoid; Q9D9B7; -.
DR OMA; HRRIAHD; -.
DR OrthoDB; 990675at2759; -.
DR TreeFam; TF338772; -.
DR BioGRID-ORCS; 76627; 3 hits in 71 CRISPR screens.
DR PRO; PR:Q9D9B7; -.
DR Proteomes; UP000000589; Chromosome 14.
DR RNAct; Q9D9B7; protein.
DR Bgee; ENSMUSG00000042888; Expressed in seminiferous tubule of testis and 10 other tissues.
DR Genevisible; Q9D9B7; MM.
DR InterPro; IPR031461; DUF4679.
DR PANTHER; PTHR22235; PTHR22235; 1.
DR Pfam; PF15728; DUF4679; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..401
FT /note="Proline-rich protein 30"
FT /id="PRO_0000312278"
FT REGION 69..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 384..401
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 133
FT /note="S -> T (in Ref. 1; BAB24878)"
FT /evidence="ECO:0000305"
FT CONFLICT 204
FT /note="K -> R (in Ref. 1; BAB24878)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 401 AA; 43406 MW; E1E63DB1779F0663 CRC64;
MLPVNKDQVL LQNTVPPGCP PQVLSQFVNS PAPNLASLCP HPTLPSSHFP LPAPPQAYFF
SSLTQTHSPG PHFSSDSNSD FVPPHSSSHP RSSSCFGQNY TYFGEKLPSP HSISPSNYQL
CVSPPLTGSS SLSQLQHSSP HSCQSPSRLQ DLQSPKITSP VPSSPSPRIQ NNKQTWQWPQ
SGSIKSSRGA GVCVPSKVDP AEFKDSGTLT QALVDHVGRR RIARDLQIQF LQRLWLGTPG
HAPVVEYPIC LVCLQIRTPS CPTPKYKTVP QLLAFPQLLP CVQGQESGPL RIGIGFGLRL
PRGQARALHL LPPKNSTPVG VESQEEALQR QKSTIQESVQ ITGTLFQARS LRSIDLQSPK
PSQCSRSLLQ EPRQVAASPK AGPSVSKRSV TLGSILRKSP S
