PRR32_HUMAN
ID PRR32_HUMAN Reviewed; 298 AA.
AC B1ATL7;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 08-APR-2008, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=Proline-rich protein 32;
GN Name=PRR32; Synonyms=CXorf64;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15772651; DOI=10.1038/nature03440;
RA Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
RA Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L.,
RA Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.,
RA Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A.,
RA Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P.,
RA Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D.,
RA Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D.,
RA Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L.,
RA Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P.,
RA Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G.,
RA Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J.,
RA Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D.,
RA Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L.,
RA Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z.,
RA Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
RA Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O.,
RA Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H.,
RA Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T.,
RA Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L.,
RA Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R.,
RA Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y.,
RA Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K.,
RA Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J.,
RA Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L.,
RA Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S.,
RA Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A.,
RA Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L.,
RA Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
RA Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
RA McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S.,
RA Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C.,
RA Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S.,
RA Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V.,
RA Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K.,
RA Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
RA Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
RA Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
RA Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B.,
RA Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C.,
RA d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q.,
RA Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N.,
RA Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A.,
RA Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J.,
RA Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A.,
RA Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
RA Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L.,
RA Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S.,
RA Rogers J., Bentley D.R.;
RT "The DNA sequence of the human X chromosome.";
RL Nature 434:325-337(2005).
CC -!- INTERACTION:
CC B1ATL7; Q86UW9: DTX2; NbExp=3; IntAct=EBI-18587059, EBI-740376;
CC B1ATL7; O95967: EFEMP2; NbExp=3; IntAct=EBI-18587059, EBI-743414;
CC B1ATL7; P52597: HNRNPF; NbExp=3; IntAct=EBI-18587059, EBI-352986;
CC B1ATL7; Q9BYJ9: YTHDF1; NbExp=3; IntAct=EBI-18587059, EBI-1051237;
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DR EMBL; AL662896; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS48163.1; -.
DR RefSeq; NP_001116188.1; NM_001122716.1.
DR AlphaFoldDB; B1ATL7; -.
DR BioGRID; 934805; 5.
DR IntAct; B1ATL7; 4.
DR STRING; 9606.ENSP00000360166; -.
DR iPTMnet; B1ATL7; -.
DR PhosphoSitePlus; B1ATL7; -.
DR BioMuta; PRR32; -.
DR PaxDb; B1ATL7; -.
DR PRIDE; B1ATL7; -.
DR Antibodypedia; 57821; 4 antibodies from 4 providers.
DR DNASU; 100130613; -.
DR Ensembl; ENST00000371125.4; ENSP00000360166.3; ENSG00000183631.5.
DR GeneID; 100130613; -.
DR KEGG; hsa:100130613; -.
DR MANE-Select; ENST00000371125.4; ENSP00000360166.3; NM_001122716.2; NP_001116188.1.
DR UCSC; uc010nra.4; human.
DR CTD; 100130613; -.
DR DisGeNET; 100130613; -.
DR GeneCards; PRR32; -.
DR HGNC; HGNC:34498; PRR32.
DR HPA; ENSG00000183631; Tissue enriched (tongue).
DR neXtProt; NX_B1ATL7; -.
DR OpenTargets; ENSG00000183631; -.
DR PharmGKB; PA162383082; -.
DR VEuPathDB; HostDB:ENSG00000183631; -.
DR eggNOG; ENOG502T9EE; Eukaryota.
DR GeneTree; ENSGT00390000012726; -.
DR HOGENOM; CLU_933713_0_0_1; -.
DR InParanoid; B1ATL7; -.
DR OMA; CFIPPRP; -.
DR OrthoDB; 1300193at2759; -.
DR PhylomeDB; B1ATL7; -.
DR TreeFam; TF338131; -.
DR PathwayCommons; B1ATL7; -.
DR SignaLink; B1ATL7; -.
DR BioGRID-ORCS; 100130613; 11 hits in 688 CRISPR screens.
DR GenomeRNAi; 100130613; -.
DR Pharos; B1ATL7; Tdark.
DR PRO; PR:B1ATL7; -.
DR Proteomes; UP000005640; Chromosome X.
DR RNAct; B1ATL7; protein.
DR Bgee; ENSG00000183631; Expressed in right cardiac atrium and 40 other tissues.
DR Genevisible; B1ATL7; HS.
DR InterPro; IPR027891; DUF4645.
DR PANTHER; PTHR37343; PTHR37343; 1.
DR Pfam; PF15488; DUF4645; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..298
FT /note="Proline-rich protein 32"
FT /id="PRO_0000336102"
FT REGION 36..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VARIANT 115
FT /note="L -> V (in dbSNP:rs12835991)"
FT /id="VAR_061638"
FT VARIANT 193
FT /note="M -> T (in dbSNP:rs4289953)"
FT /id="VAR_059650"
SQ SEQUENCE 298 AA; 31890 MW; 4CE1F2CB6F195D28 CRC64;
MACIENVLGG HAPSPLVVSV DKNGNQELHH DMPLQCLSSK PEDDAEPWGQ PQVPLRPSVN
VLTDLDSKQL EWPSERTGSC IPLHSLRAHR HPYGPPPAVA EESLATAEVN SSDALAGWRQ
EGQDAINVSW EVSGGPPALI VGGTKVNNGG TERGSNNARL HVALPQGKGF FPPRGPQVRG
PSHIPTLRSG IVMEVPPGNT RIACRGKLAH VSFPLRGPCH PMHNWPRPIP LSSSTPGLPS
CSTVHCFIPP RPPIFNPFLT MPLPFAPPPI FGPPLPSYFA HFHSGGMPAP ASPNREHS
