PRR5_XENLA
ID PRR5_XENLA Reviewed; 400 AA.
AC Q8AVJ1;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 46.
DE RecName: Full=Proline-rich protein 5;
DE AltName: Full=Protein observed with Rictor-1;
DE Short=Protor-1;
GN Name=prr5; Synonyms=protor1;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RA Klein S., Strausberg R.;
RL Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Subunit of TORC2, which regulates cell growth and survival in
CC response to hormonal signals. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PROTOR family. {ECO:0000305}.
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DR EMBL; BC042252; AAH42252.1; -; mRNA.
DR RefSeq; NP_001080344.1; NM_001086875.1.
DR AlphaFoldDB; Q8AVJ1; -.
DR SMR; Q8AVJ1; -.
DR PRIDE; Q8AVJ1; -.
DR DNASU; 380036; -.
DR GeneID; 380036; -.
DR KEGG; xla:380036; -.
DR CTD; 380036; -.
DR Xenbase; XB-GENE-5918844; prr5.L.
DR OrthoDB; 1260193at2759; -.
DR Proteomes; UP000186698; Chromosome 3L.
DR Bgee; 380036; Expressed in kidney and 19 other tissues.
DR InterPro; IPR013745; Bit61/PRR5.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR PANTHER; PTHR32428; PTHR32428; 1.
DR Pfam; PF08539; HbrB; 1.
DR SUPFAM; SSF74788; SSF74788; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..400
FT /note="Proline-rich protein 5"
FT /id="PRO_0000332712"
FT REGION 301..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..358
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 400 AA; 44563 MW; 8C5A7071A7E0EDC2 CRC64;
MRSKFMSSPT LSDLGKREAT AAAALDERGT QQKRAGANAT WNSIQNGVIS VFQKKGLADH
ELYSLNEGVR QLLKTELGSF FTEYLQNQLL TKGMVILRDK IRFYEGQKLL DSLAETWDFF
FSDILPMLQA IFYPVQGKEP SIRQLALLHF RNIITLNLKL DDALSRPRAR VPPSIIQMLL
ILQGVHESKG VTEEYMNLES LIQKVVSPYL GTYGLYSNEA PFCHSSCILE KRMFRRCPKS
GEILTKNPVV RSKSYNNPLL TPVAEYEMEN LVANGSGIRR HSVSEMTSVL ELPMGYSNLT
TDSTSKLSMA GTKPPGEGER PPISNGQFPP LHNLSDSQQG LYNSQRDSPL LPAPSSSPET
IVDQILESID SDSEGIFIDF GRGCSKSPEF SMEIGRQSLV