ID   PRRC1_DANRE             Reviewed;         435 AA.
AC   Q5XJA3; A5LID3;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 2.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Protein PRRC1;
DE   AltName: Full=Proline-rich and coiled-coil-containing protein 1;
DE   AltName: Full=Protein misty somites;
GN   Name=prrc1; Synonyms=mys; ORFNames=zgc:103484;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=18342848; DOI=10.1016/j.ydbio.2008.01.043;
RA   Kotani T., Kawakami K.;
RT   "Misty somites, a maternal effect gene identified by transposon-mediated
RT   insertional mutagenesis in zebrafish that is essential for the somite
RT   boundary maintenance.";
RL   Dev. Biol. 316:383-396(2008).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PRRC1 family. {ECO:0000305}.
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DR   EMBL; AB307684; BAF63642.1; -; mRNA.
DR   EMBL; BC083401; AAH83401.1; -; mRNA.
DR   RefSeq; NP_001007061.2; NM_001007060.2.
DR   RefSeq; XP_005155630.1; XM_005155573.3.
DR   AlphaFoldDB; Q5XJA3; -.
DR   SMR; Q5XJA3; -.
DR   STRING; 7955.ENSDARP00000065044; -.
DR   PaxDb; Q5XJA3; -.
DR   Ensembl; ENSDART00000065045; ENSDARP00000065044; ENSDARG00000044304.
DR   Ensembl; ENSDART00000175513; ENSDARP00000144236; ENSDARG00000044304.
DR   GeneID; 474330; -.
DR   KEGG; dre:474330; -.
DR   CTD; 133619; -.
DR   ZFIN; ZDB-GENE-041024-9; prrc1.
DR   eggNOG; ENOG502QUZV; Eukaryota.
DR   GeneTree; ENSGT00390000003837; -.
DR   HOGENOM; CLU_041959_0_0_1; -.
DR   InParanoid; Q5XJA3; -.
DR   OMA; VTRTDWH; -.
DR   OrthoDB; 930508at2759; -.
DR   PhylomeDB; Q5XJA3; -.
DR   TreeFam; TF343676; -.
DR   PRO; PR:Q5XJA3; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 10.
DR   Bgee; ENSDARG00000044304; Expressed in blastula and 32 other tissues.
DR   ExpressionAtlas; Q5XJA3; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IDA:ZFIN.
DR   GO; GO:0005794; C:Golgi apparatus; IDA:ZFIN.
DR   GO; GO:0034237; F:protein kinase A regulatory subunit binding; IDA:ZFIN.
DR   GO; GO:0034199; P:activation of protein kinase A activity; IDA:ZFIN.
DR   GO; GO:0010669; P:epithelial structure maintenance; IMP:ZFIN.
DR   GO; GO:0001757; P:somite specification; IMP:ZFIN.
DR   Gene3D; 3.90.950.10; -; 1.
DR   InterPro; IPR029001; ITPase-like_fam.
DR   InterPro; IPR026533; NTPase/PRRC1.
DR   InterPro; IPR026534; PRRC1.
DR   PANTHER; PTHR23276; PTHR23276; 1.
DR   Pfam; PF01931; NTPase_I-T; 1.
DR   SUPFAM; SSF52972; SSF52972; 1.
PE   2: Evidence at transcript level;
KW   Golgi apparatus; Reference proteome.
FT   CHAIN           1..435
FT                   /note="Protein PRRC1"
FT                   /id="PRO_0000307342"
FT   REGION          1..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          101..165
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..24
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        25..54
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        104..121
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        147..165
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        6
FT                   /note="G -> D (in Ref. 1; BAF63642)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        8
FT                   /note="E -> K (in Ref. 2; AAH83401)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        187
FT                   /note="D -> N (in Ref. 1; BAF63642)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        353
FT                   /note="F -> S (in Ref. 1; BAF63642)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   435 AA;  45390 MW;  DABBCC0AC3D8EAB5 CRC64;
     MMEESGIEST PPATPPPPST VVASPPPLTS GATRPQTVPS PSGISAFTPG DFSSPVPSVA
     LTSTLPPMQS SVPPLPLSSI SSPLGLSGPY GIPSASFASP AAGPPLSTGP PLGPVLSAPP
     MGPPTTGFSV SGGYDITRGH AGRTPQTPLM PSFSSASPMP GIVTNPMMQQ PVSGGLDVSS
     PITFPEDVED PRVTPDSNAP GGLWGFIKGV AGNPMVKTVL DKTKHSVESM ITTLDPGMAP
     YIKSGGDVDI VVTSDKEVKV AAVRDAFQEV FGLAMVTGEA GQSNIAPQPV GYAAGVKGAQ
     ERIDSLRRAA VIHEKQPVVS VENFIAELFP DKWFDIGCLI LDDPGYGIHI ETFTQATPVA
     LEHVQQAQSL TPPDYNLRWS GLLVTVGEVL ERNVPNVSRT DWHQAFTGMS RRQMIYSAAK
     ALAGMYKLRL PSRTV