ID   ATG33_CANGA             Reviewed;         216 AA.
AC   Q6FXH5;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Autophagy-related protein 33;
GN   Name=ATG33; OrderedLocusNames=CAGL0B02860g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in the selective degradation of mitochondria via
CC       autophagy during starvation and at post-log phase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ATG33 family. {ECO:0000305}.
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DR   EMBL; CR380948; CAG57996.1; -; Genomic_DNA.
DR   RefSeq; XP_445096.1; XM_445096.1.
DR   AlphaFoldDB; Q6FXH5; -.
DR   STRING; 5478.XP_445096.1; -.
DR   EnsemblFungi; CAG57996; CAG57996; CAGL0B02860g.
DR   GeneID; 2886662; -.
DR   KEGG; cgr:CAGL0B02860g; -.
DR   CGD; CAL0127044; CAGL0B02860g.
DR   VEuPathDB; FungiDB:CAGL0B02860g; -.
DR   eggNOG; ENOG502S27M; Eukaryota.
DR   HOGENOM; CLU_105986_1_0_1; -.
DR   InParanoid; Q6FXH5; -.
DR   Proteomes; UP000002428; Chromosome B.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Autophagy; Membrane; Mitochondrion; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..216
FT                   /note="Autophagy-related protein 33"
FT                   /id="PRO_0000399766"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        193..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   216 AA;  23001 MW;  EAC6A64230C72925 CRC64;
     MSTCLTVTKG IAISSLGLYA GIVSAGTLLV VNDRVTPTND SKHDLVRTLL CKVGTGLNVV
     ATVVFGLVYF SSPGYARHPY LVYAALTGPA TSLYMFLSKR YWLKQLRNLK ETKITDEKHS
     PPPVGQDAAQ TSDKAEISYA AAAAVGAENG GELSESVVDL GIEKTIAQAE KDFEKQKADE
     VVRRETQSIK VRAVATAVIA TVGFIQSVIG VSGEHL