ID   PRS6A_BRACM             Reviewed;         424 AA.
AC   O23894;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=26S proteasome regulatory subunit 6A homolog;
DE   AltName: Full=Tat-binding protein homolog 1;
DE            Short=TBP-1;
GN   Name=TBP1; Synonyms=TBP;
OS   Brassica campestris (Field mustard).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX   NCBI_TaxID=3711;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Anther;
RX   PubMed=9327593; DOI=10.1093/oxfordjournals.pcp.a029259;
RA   Kitashiba H., Toriyama K.;
RT   "Expression of a gene for a protein similar to HIV-1 Tat binding protein 1
RT   (TBP1) in floral organs of Brassica rapa.";
RL   Plant Cell Physiol. 38:966-969(1997).
CC   -!- FUNCTION: The 26S proteasome is involved in the ATP-dependent
CC       degradation of ubiquitinated proteins. The regulatory (or ATPase)
CC       complex confers ATP dependency and substrate specificity to the 26S
CC       complex (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the AAA ATPase family. {ECO:0000305}.
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DR   EMBL; D88663; BAA22951.1; -; mRNA.
DR   RefSeq; XP_009124018.1; XM_009125770.2.
DR   AlphaFoldDB; O23894; -.
DR   SMR; O23894; -.
DR   STRING; 3711.Bra040214.1-P; -.
DR   EnsemblPlants; Bra040214.1; Bra040214.1-P; Bra040214.
DR   GeneID; 103848939; -.
DR   Gramene; Bra040214.1; Bra040214.1-P; Bra040214.
DR   KEGG; brp:103848939; -.
DR   OMA; WARLSSY; -.
DR   OrthoDB; 571919at2759; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0036402; F:proteasome-activating activity; IEA:InterPro.
DR   GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
DR   Gene3D; 2.40.50.140; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR005937; 26S_Psome_P45-like.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR041569; AAA_lid_3.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR003960; ATPase_AAA_CS.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR032501; Prot_ATP_ID_OB_C.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF17862; AAA_lid_3; 1.
DR   Pfam; PF16450; Prot_ATP_ID_OB; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01242; 26Sp45; 1.
DR   PROSITE; PS00674; AAA; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Cytoplasm; Isopeptide bond; Nucleotide-binding; Nucleus;
KW   Phosphoprotein; Proteasome; Ubl conjugation.
FT   CHAIN           1..424
FT                   /note="26S proteasome regulatory subunit 6A homolog"
FT                   /id="PRO_0000084704"
FT   BINDING         212..219
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         19
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9SEI4"
FT   CROSSLNK        235
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in ubiquitin)"
FT                   /evidence="ECO:0000250|UniProtKB:Q9SEI3"
FT   CROSSLNK        279
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in ubiquitin)"
FT                   /evidence="ECO:0000250|UniProtKB:Q9SEI2"
FT   CROSSLNK        416
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in ubiquitin)"
FT                   /evidence="ECO:0000250|UniProtKB:Q9SEI2"
SQ   SEQUENCE   424 AA;  47492 MW;  20401CD584E0CFFC CRC64;
     MATPMVEDTS SFEEDQLASM STEDIVRATR LLENEIRILK EDAQRTNLEC DSYKEKIKEN
     QEKIKLNKQL PYLVGNIVEI LEMNPEDDAE EDGANIDLDS QRKGKCVVLK TSTRQTIFLP
     VVGLVDPDSL KPGDLVGVNK DSYLILDTLP SEYDSRVKAM EVDEKPTEDY NDIGGLEKQI
     QELVEAIVLP MTHKERFEKL GVRPPKGVLL YGPPGTGKTL MARACAAQTN ATFLKLAGPQ
     LVQMFIGDGA KLVRDAFQLA KEKAPCIIFI DEIDAIGTKR FDSEVSGDRE VQRTMLELLN
     QLDGFSSDER IKVIAATNRA DILDPALMRS GRLDRKIEFP HPTEEARARI LQIHSRKMNV
     HPDVNFEELA RSTDDFNGAQ LKAVCVEAGM LALRRDATEV NHEDFNEGII QVQAKKKASL
     NYYA