ID   PRS6B_SOLTU             Reviewed;         413 AA.
AC   P54778;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=26S proteasome regulatory subunit 6B homolog;
OS   Solanum tuberosum (Potato).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX   NCBI_TaxID=4113;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Superior;
RA   Hart J.K., Hannapel D.J.;
RT   "Isolation of an AAA superfamily cDNA clone from potato.";
RL   (er) Plant Gene Register PGR96-039(1996).
CC   -!- FUNCTION: The 26S proteasome is involved in the ATP-dependent
CC       degradation of ubiquitinated proteins. The regulatory (or ATPase)
CC       complex confers ATP dependency and substrate specificity to the 26S
CC       complex (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the AAA ATPase family. {ECO:0000305}.
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DR   EMBL; U43398; AAB67835.1; -; mRNA.
DR   PIR; T07110; T07110.
DR   RefSeq; NP_001275060.1; NM_001288131.1.
DR   AlphaFoldDB; P54778; -.
DR   SMR; P54778; -.
DR   STRING; 4113.PGSC0003DMT400053010; -.
DR   ProMEX; P54778; -.
DR   GeneID; 102577768; -.
DR   KEGG; sot:102577768; -.
DR   eggNOG; KOG0727; Eukaryota.
DR   OrthoDB; 571919at2759; -.
DR   Proteomes; UP000011115; Unassembled WGS sequence.
DR   ExpressionAtlas; P54778; baseline.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008540; C:proteasome regulatory particle, base subcomplex; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0036402; F:proteasome-activating activity; IBA:GO_Central.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   Gene3D; 2.40.50.140; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR005937; 26S_Psome_P45-like.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR041569; AAA_lid_3.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR003960; ATPase_AAA_CS.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR032501; Prot_ATP_ID_OB_C.
DR   InterPro; IPR035256; PSMC4.
DR   PANTHER; PTHR23073:SF120; PTHR23073:SF120; 1.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF17862; AAA_lid_3; 1.
DR   Pfam; PF16450; Prot_ATP_ID_OB; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01242; 26Sp45; 1.
DR   PROSITE; PS00674; AAA; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Coiled coil; Cytoplasm; Nucleotide-binding; Nucleus;
KW   Proteasome; Reference proteome.
FT   CHAIN           1..413
FT                   /note="26S proteasome regulatory subunit 6B homolog"
FT                   /id="PRO_0000084693"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          32..80
FT                   /evidence="ECO:0000255"
FT   BINDING         201..208
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   413 AA;  46532 MW;  C6DC13DF0903F385 CRC64;
     MATAMVLDPK PAEKLPATRP ETSITDVPSD GEDDLYARLK SLQRQLEFIE IQEEYVKDEL
     KNLRREHLRA QEEVKRIQSV PLVIGQFMEM IDQNNAIVGS TTGSNYYVRI LSTINRELLK
     PSASVGLDRH SNALVDVLPP EADSSISLLS QSEKPDVTYN DIGGCDIQKQ EIREAVELPL
     THHELYKQIG IDPPRGVLLY GPPGTGKTML AKAVAHHTTA AFIRVVGSEF VQKYLGEGPR
     MVRDVFRLAK ENAPAIIFID EVDAIATARF DAQTGADREV QRILMELLNQ MDGFDQTVNV
     KVIMATNRAD TLDPALLRPG RLDRKIEFPL PDRRQKRLVF QVCTAKMNLG DEVDLEDYVS
     RPDKISAAEI TAICQEAGMH AVRKNRYVIL PKDFEKGYRT NVKKPDTDFE FYK