PRSA_ECOLX
ID PRSA_ECOLX Reviewed; 161 AA.
AC P42184;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=PRS fimbrial major pilin protein;
DE Short=PRS pili;
DE Flags: Fragment;
GN Name=prsA;
OS Escherichia coli.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=1442;
RX PubMed=1357526; DOI=10.1111/j.1365-2958.1992.tb01399.x;
RA Marklund B.-I., Tennent J.M., Garcia E., Hamers A., Baga M., Lindberg F.,
RA Gaastra W., Normark S.;
RT "Horizontal gene transfer of the Escherichia coli pap and prs pili operons
RT as a mechanism for the development of tissue-specific adhesive
RT properties.";
RL Mol. Microbiol. 6:2225-2242(1992).
CC -!- FUNCTION: Fimbriae (also called pili), polar filaments radiating from
CC the surface of the bacterium to a length of 0.5-1.5 micrometers and
CC numbering 100-300 per cell, enable bacteria to colonize the epithelium
CC of specific host organs.
CC -!- INTERACTION:
CC P42184; P75869: sxy; Xeno; NbExp=2; IntAct=EBI-544466, EBI-544452;
CC -!- SUBCELLULAR LOCATION: Secreted. Fimbrium.
CC -!- SIMILARITY: Belongs to the fimbrial protein family. {ECO:0000305}.
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DR EMBL; X62157; CAA44083.1; -; Genomic_DNA.
DR PIR; S25206; S25206.
DR AlphaFoldDB; P42184; -.
DR SMR; P42184; -.
DR IntAct; P42184; 46.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR Gene3D; 2.60.40.1090; -; 1.
DR InterPro; IPR000259; Adhesion_dom_fimbrial.
DR InterPro; IPR036937; Adhesion_dom_fimbrial_sf.
DR InterPro; IPR008966; Adhesion_dom_sf.
DR Pfam; PF00419; Fimbrial; 1.
DR SUPFAM; SSF49401; SSF49401; 1.
PE 1: Evidence at protein level;
KW Fimbrium; Secreted.
FT CHAIN <1..161
FT /note="PRS fimbrial major pilin protein"
FT /id="PRO_0000196349"
FT NON_TER 1
SQ SEQUENCE 161 AA; 16361 MW; 1245036C9E6FBC13 CRC64;
GANAAPQGQG KVTFNGTVVD APCGIDAQSA DQSIEFGQVS KVLLNNGGSS TPKNFDIKLT
DCDVTNYKKA GKAGTVSLTF SGVQAGTDML QTVGTTGTAI LVKDPHGKAV KFDGATATGV
SSLVDGDNTI HFTALVKKDT SGNDVAEGAF SAVANFNLIY Q