ID   PRSE_RHIME              Reviewed;         439 AA.
AC   Q7ANN5; O33679;
DT   25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT   16-NOV-2011, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Type I secretion system membrane fusion protein PrsE;
GN   Name=prsE; OrderedLocusNames=RB1291; ORFNames=SM_b21465;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OG   Plasmid pSymB (megaplasmid 2).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND SUBUNIT.
RC   STRAIN=1021;
RX   PubMed=11902715; DOI=10.1046/j.1365-2958.1997.4481804.x;
RA   York G.M., Walker G.C.;
RT   "The Rhizobium meliloti exoK gene and prsD/prsE/exsH genes encode
RT   components of independent degradative pathways which contribute to
RT   production of low-molecular-weight succinoglycan.";
RL   Mol. Microbiol. 25:117-134(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481431; DOI=10.1073/pnas.161294698;
RA   Finan T.M., Weidner S., Wong K., Buhrmester J., Chain P., Vorhoelter F.J.,
RA   Hernandez-Lucas I., Becker A., Cowie A., Gouzy J., Golding B., Puehler A.;
RT   "The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing
RT   endosymbiont Sinorhizobium meliloti.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9889-9894(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- FUNCTION: Mediates secretion of glycanase ExsH.
CC       {ECO:0000269|PubMed:11902715}.
CC   -!- SUBUNIT: Part of a type I secretion system composed of PrsD and PrsE.
CC       {ECO:0000305|PubMed:11902715}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Single-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000305}.
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DR   EMBL; U89163; AAB64092.1; -; Genomic_DNA.
DR   EMBL; AL591985; CAC49691.1; -; Genomic_DNA.
DR   PIR; C96003; C96003.
DR   RefSeq; NP_437831.1; NC_003078.1.
DR   RefSeq; WP_010976110.1; NC_003078.1.
DR   AlphaFoldDB; Q7ANN5; -.
DR   SMR; Q7ANN5; -.
DR   STRING; 266834.SM_b21465; -.
DR   EnsemblBacteria; CAC49691; CAC49691; SM_b21465.
DR   GeneID; 61601214; -.
DR   KEGG; sme:SM_b21465; -.
DR   PATRIC; fig|266834.11.peg.6214; -.
DR   eggNOG; COG0845; Bacteria.
DR   HOGENOM; CLU_023976_1_1_5; -.
DR   OMA; DQMRHAF; -.
DR   Proteomes; UP000001976; Plasmid pSymB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR043602; CusB_dom_1.
DR   InterPro; IPR032317; HlyD_D23.
DR   InterPro; IPR010129; T1SS_HlyD.
DR   Pfam; PF00529; CusB_dom_1; 1.
DR   Pfam; PF16576; HlyD_D23; 1.
DR   TIGRFAMs; TIGR01843; type_I_hlyD; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Plasmid; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..439
FT                   /note="Type I secretion system membrane fusion protein
FT                   PrsE"
FT                   /id="PRO_0000415268"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   439 AA;  48036 MW;  82B2421825522DBD CRC64;
     MKGWLQQHKP TARRSLSRHL IGVSVLALAL VAGVGGWAAT TELSSAIVAG GVVIVDDNVK
     KVQHLTGGIV GELLVKEGDR VEAGQVLIRL DGTTVRANLA IIESTLAQFY ARRARLQAER
     MGAASFEIEE DLAEFIPGTA AAKLIEGEQR LFASRRSALS GMKGQLDSRK AQLADEVEGL
     TVQLNAIEEA LKLIAEELTG VDSLFGQGLV PMQRVTTLKR QRAELEGGRG RHIAARAQAR
     GKSSEIDLQI LQLDEDRRSE ISKELTDVEA KIAEYEERRT AATDQLRRLD ITAPLSGRIY
     QLAIHTVNGV INPGETLMLV VPEAEDLTVE AKVATHDIDQ IRVGQSVEIR FSAFNQRTTP
     EVEAEVVTVA PDLVTDERTG ASYYPLRIRP KAESLAKLKG LSLYPGMPAE VFIKIADRTV
     ISYLTKPLTD QMRHAFRED