ID   PRS_GALME               Reviewed;          20 AA.
AC   C0HLY5;
DT   23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT   23-FEB-2022, sequence version 1.
DT   03-AUG-2022, entry version 3.
DE   RecName: Full=Putative serine protease {ECO:0000303|PubMed:34443685};
DE            EC=3.4.21.- {ECO:0000250|UniProtKB:Q9V3Z2};
DE   Flags: Fragment;
OS   Galleria mellonella (Greater wax moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Pyraloidea;
OC   Pyralidae; Galleriinae; Galleria.
OX   NCBI_TaxID=7137;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, SUBCELLULAR LOCATION, AND DEVELOPMENTAL STAGE.
RX   PubMed=34443685; DOI=10.3390/molecules26165097;
RA   Staczek S., Zdybicka-Barabas A., Wojda I., Wiater A., Mak P., Suder P.,
RA   Skrzypiec K., Cytrynska M.;
RT   "Fungal alpha-1,3-Glucan as a New Pathogen-Associated Molecular Pattern in
RT   the Insect Model Host Galleria mellonella.";
RL   Molecules 26:5097-5097(2021).
CC   -!- FUNCTION: Binds the A.niger cell wall component alpha-1,3-glucan, a
CC       fungal pathogen-associated molecular pattern (PAMP) that activates the
CC       host immune response. {ECO:0000269|PubMed:34443685}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:34443685}.
CC       Note=Secreted in the hemolymph. {ECO:0000269|PubMed:34443685}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in last instar larvae.
CC       {ECO:0000269|PubMed:34443685}.
CC   -!- SIMILARITY: Belongs to the peptidase S1 family. {ECO:0000305}.
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DR   Proteomes; UP000504614; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Hydrolase; Immunity; Innate immunity; Protease;
KW   Reference proteome; Secreted; Serine protease.
FT   CHAIN           <1..>20
FT                   /note="Putative serine protease"
FT                   /id="PRO_0000455046"
FT   NON_TER         1
FT                   /evidence="ECO:0000303|PubMed:34443685"
FT   NON_TER         20
FT                   /evidence="ECO:0000303|PubMed:34443685"
SQ   SEQUENCE   20 AA;  2258 MW;  F3E99A15346D6C74 CRC64;
     LKDGPCPSYM DTCCLSPDRR