ID   PRT1A_ONCMY             Reviewed;          31 AA.
AC   P12819;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Protamine-1A;
DE   AltName: Full=Protamine PRTP43/PPC 2E;
OS   Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Oncorhynchus.
OX   NCBI_TaxID=8022;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (CLONE PRTP43).
RX   PubMed=6262730; DOI=10.1093/nar/9.6.1463;
RA   Gedamu L., Wosnick M.A., Connor W., Watson D.C., Dixon G.H., Iatrou K.;
RT   "Molecular analysis of the protamine multi-gene family in rainbow trout
RT   testis.";
RL   Nucleic Acids Res. 9:1463-1482(1981).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] (CLONE PPC 2E).
RX   PubMed=7287661; DOI=10.1093/oxfordjournals.jbchem.a133388;
RA   Sakai M., Fujii-Kuriyama Y., Saito T., Muramatsu M.;
RT   "Closely related mRNA sequences of protamines in rainbow trout testis.";
RL   J. Biochem. 89:1863-1868(1981).
RN   [3]
RP   PROTEIN SEQUENCE OF 2-31.
RX   PubMed=3755398; DOI=10.1111/j.1432-1033.1986.tb09759.x;
RA   McKay D.J., Renaux B.S., Dixon G.H.;
RT   "Rainbow trout protamines. Amino acid sequences of six distinct proteins
RT   from a single testis.";
RL   Eur. J. Biochem. 158:361-366(1986).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Testis.
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DR   EMBL; K03052; AAA49607.1; -; mRNA.
DR   EMBL; K03051; AAA49606.1; -; mRNA.
DR   PIR; B02673; IRTRC2.
DR   PIR; I51349; I51349.
DR   AlphaFoldDB; P12819; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Chromosome; Developmental protein; Differentiation;
KW   Direct protein sequencing; DNA condensation; DNA-binding; Nucleosome core;
KW   Nucleus; Spermatogenesis.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:3755398"
FT   PEPTIDE         2..31
FT                   /note="Protamine-1A"
FT                   /id="PRO_0000044310"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   31 AA;  4181 MW;  C74CBF9DC78B1093 CRC64;
     MPRRRRASRR VRRRRRPRVS RRRRRGGRRR R