ID   PRT1_ONCKE              Reviewed;          33 AA.
AC   P69014; P02327;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=Protamine;
DE   AltName: Full=Salmine-AI;
OS   Oncorhynchus keta (Chum salmon) (Salmo keta).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Oncorhynchus.
OX   NCBI_TaxID=8018;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2838640; DOI=10.1007/bf02099725;
RA   Moir R.D., Dixon G.H.;
RT   "Characterization of a protamine gene from the chum salmon (Oncorhynchus
RT   keta).";
RL   J. Mol. Evol. 27:8-16(1988).
RN   [2]
RP   PROTEIN SEQUENCE OF 2-33.
RX   PubMed=4953052; DOI=10.1111/j.1399-3011.1969.tb01646.x;
RA   Ando T., Watanabe S.;
RT   "A new method for fractionation of protamines and the amino acid sequences
RT   of salmine and three components of iridine.";
RL   Int. J. Protein Res. 1:221-224(1969).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Testis.
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DR   EMBL; X07511; CAA30391.1; -; Genomic_DNA.
DR   PIR; A02669; SLONA1.
DR   PIR; S00710; S00710.
DR   AlphaFoldDB; P69014; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Chromosome; Developmental protein; Differentiation;
KW   Direct protein sequencing; DNA condensation; DNA-binding; Nucleosome core;
KW   Nucleus; Spermatogenesis.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:4953052"
FT   PEPTIDE         2..33
FT                   /note="Protamine"
FT                   /id="PRO_0000044836"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   33 AA;  4381 MW;  CC93956D90B796EA CRC64;
     MPRRRRSSSR PVRRRRRPRV SRRRRRRGGR RRR