PRT3A_ONCMY
ID PRT3A_ONCMY Reviewed; 32 AA.
AC P12818;
DT 01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1989, sequence version 1.
DT 25-MAY-2022, entry version 52.
DE RecName: Full=Protamine-3A;
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=3755398; DOI=10.1111/j.1432-1033.1986.tb09759.x;
RA McKay D.J., Renaux B.S., Dixon G.H.;
RT "Rainbow trout protamines. Amino acid sequences of six distinct proteins
RT from a single testis.";
RL Eur. J. Biochem. 158:361-366(1986).
CC -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC during the haploid phase of spermatogenesis. They compact sperm DNA
CC into a highly condensed, stable and inactive complex.
CC -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC -!- TISSUE SPECIFICITY: Testis.
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DR PIR; F24970; F24970.
DR AlphaFoldDB; P12818; -.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Chromosome; Developmental protein; Differentiation;
KW Direct protein sequencing; DNA condensation; DNA-binding; Nucleosome core;
KW Nucleus; Spermatogenesis.
FT PEPTIDE 1..32
FT /note="Protamine-3A"
FT /id="PRO_0000044843"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 32 AA; 4264 MW; 58FB9D8CD1E648F5 CRC64;
PRRRRRSSSR PIRRRRRPRV SRRRRRGGRR RR