PRT4_ONCMY
ID PRT4_ONCMY Reviewed; 31 AA.
AC P02333;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 25-MAY-2022, entry version 53.
DE RecName: Full=Protamine PTP4;
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=450133; DOI=10.1038/279809a0;
RA Jenkins J.R.;
RT "Sequence divergence of rainbow trout protamine mRNAs; comparison of coding
RT and non-coding nucleotide sequences in three protamine cDNA plasmids.";
RL Nature 279:809-811(1979).
CC -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC during the haploid phase of spermatogenesis. They compact sperm DNA
CC into a highly condensed, stable and inactive complex.
CC -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC -!- TISSUE SPECIFICITY: Testis.
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DR EMBL; X01204; CAA25623.1; -; mRNA.
DR PIR; A02675; IRTR4.
DR AlphaFoldDB; P02333; -.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
PE 2: Evidence at transcript level;
KW Chromosome; Developmental protein; Differentiation; DNA condensation;
KW DNA-binding; Nucleosome core; Nucleus; Spermatogenesis.
FT INIT_MET 1
FT /note="Removed"
FT PEPTIDE 2..31
FT /note="Protamine PTP4"
FT /id="PRO_0000044309"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 31 AA; 4195 MW; C74CBF9DCD97DCE3 CRC64;
MPRRRRASRR IRRRRRPRVS RRRRGGRRRR R