ID   PRTA_ACIST              Reviewed;          27 AA.
AC   P02324;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Protamine-A;
DE   AltName: Full=Stellin-A;
DE   Contains:
DE     RecName: Full=Protamine-C;
DE     AltName: Full=Stellin-C;
OS   Acipenser stellatus (Sevruga) (Starry sturgeon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Chondrostei; Acipenseriformes; Acipenseridae; Acipenser.
OX   NCBI_TaxID=7903;
RN   [1]
RP   PROTEIN SEQUENCE.
RA   Yulikova E.P., Rybin V.K., Silaev A.B.;
RT   "The primary structure of stellin A.";
RL   Bioorg. Khim. 5:5-10(1979).
RN   [2]
RP   PROTEIN SEQUENCE OF 2-27.
RX   PubMed=1339950;
RA   Rybin V.K., Revina L.P., Baratova L.A.;
RT   "Comparison of amino acid sequences of sturgeon triprotamines using
RT   protamines from Acipenser stellatus gonads as an example.";
RL   Mol. Biol. (Mosk.) 26:300-306(1992).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Testis.
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DR   PIR; A02666; SRAPAS.
DR   AlphaFoldDB; P02324; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Chromosome; Developmental protein; Differentiation;
KW   Direct protein sequencing; DNA condensation; DNA-binding; Nucleosome core;
KW   Nucleus; Spermatogenesis.
FT   PEPTIDE         1..27
FT                   /note="Protamine-A"
FT                   /id="PRO_0000025821"
FT   PEPTIDE         2..27
FT                   /note="Protamine-C"
FT                   /id="PRO_0000025822"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   27 AA;  3532 MW;  3EAA45B950FA8658 CRC64;
     ARRRRRHAST KLKRRRRRRR HGKKSHK