ID   PRTC3_ONCMY             Reviewed;          31 AA.
AC   P02331;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Protamine CIII;
DE   AltName: Full=Protamine PPC 6B;
OS   Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Oncorhynchus.
OX   NCBI_TaxID=8022;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (CLONE CIII).
RX   PubMed=6262730; DOI=10.1093/nar/9.6.1463;
RA   Gedamu L., Wosnick M.A., Connor W., Watson D.C., Dixon G.H., Iatrou K.;
RT   "Molecular analysis of the protamine multi-gene family in rainbow trout
RT   testis.";
RL   Nucleic Acids Res. 9:1463-1482(1981).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] (CLONE PPC 6B).
RX   PubMed=7287661; DOI=10.1093/oxfordjournals.jbchem.a133388;
RA   Sakai M., Fujii-Kuriyama Y., Saito T., Muramatsu M.;
RT   "Closely related mRNA sequences of protamines in rainbow trout testis.";
RL   J. Biochem. 89:1863-1868(1981).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Testis.
CC   -!- MISCELLANEOUS: The protamine CIII/PPC 6B sequence is shown.
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DR   EMBL; K03052; -; NOT_ANNOTATED_CDS; mRNA.
DR   PIR; A02673; IRTRC3.
DR   AlphaFoldDB; P02331; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Chromosome; Developmental protein; Differentiation; DNA condensation;
KW   DNA-binding; Nucleosome core; Nucleus; Spermatogenesis.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   PEPTIDE         2..31
FT                   /note="Protamine CIII"
FT                   /id="PRO_0000044307"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VARIANT         11
FT                   /note="V -> I (in 18% of the CIII)"
FT   VARIANT         11
FT                   /note="V -> P (in 18% of the CIII)"
SQ   SEQUENCE   31 AA;  4122 MW;  C74CBF9DC788A673 CRC64;
     MPRRRRASRP VRRRRRPRVS RRRRRGGRRR R