PRTIB_ONCMY
ID PRTIB_ONCMY Reviewed; 33 AA.
AC P02326;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 25-MAY-2022, entry version 53.
DE RecName: Full=Protamine-1B;
DE AltName: Full=Iridine IB;
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=4953052; DOI=10.1111/j.1399-3011.1969.tb01646.x;
RA Ando T., Watanabe S.;
RT "A new method for fractionation of protamines and the amino acid sequences
RT of salmine and three components of iridine.";
RL Int. J. Protein Res. 1:221-224(1969).
CC -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC during the haploid phase of spermatogenesis. They compact sperm DNA
CC into a highly condensed, stable and inactive complex.
CC -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC -!- TISSUE SPECIFICITY: Testis.
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DR PIR; A02668; IRTR1B.
DR AlphaFoldDB; P02326; -.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Chromosome; Developmental protein; Differentiation;
KW Direct protein sequencing; DNA condensation; DNA-binding; Nucleosome core;
KW Nucleus; Spermatogenesis.
FT PEPTIDE 1..33
FT /note="Protamine-1B"
FT /id="PRO_0000044844"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 33 AA; 4420 MW; C859FA8CD1E64A7F CRC64;
PRRRRRRSSS RPIRRRRPRR VSRRRRRGGR RRR