ID   PRTS4_SCYCA             Reviewed;          32 AA.
AC   P30259;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Protamine S4;
OS   Scyliorhinus canicula (Small-spotted catshark) (Squalus canicula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC   Scyliorhinus.
OX   NCBI_TaxID=7830;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Testis;
RA   Sautiere P., Gusse M., Briand G., Martinage A., Chevaillier P.;
RT   "Primary structure of scylliorhinine S4, a protamine isolated from sperm
RT   nuclei of the dog-fish Scylliorhinus caniculus.";
RL   Biochim. Biophys. Acta 791:82-86(1984).
RN   [2]
RP   PROTEIN SEQUENCE OF 1-5.
RX   PubMed=6615852; DOI=10.1016/0167-4838(83)90031-6;
RA   Gusse M., Sautiere P., Chauviere M., Chevaillier P.;
RT   "Extraction, purification and characterization of the sperm protamines of
RT   the dog-fish Scylliorhinus caniculus.";
RL   Biochim. Biophys. Acta 748:93-98(1983).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Testis.
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DR   PIR; A41270; A41270.
DR   AlphaFoldDB; P30259; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Chromosome; Developmental protein; Differentiation;
KW   Direct protein sequencing; DNA condensation; DNA-binding; Nucleosome core;
KW   Nucleus; Spermatogenesis.
FT   PEPTIDE         1..32
FT                   /note="Protamine S4"
FT                   /id="PRO_0000044851"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   32 AA;  3882 MW;  4C4E9F58958D1AEF CRC64;
     GCKKRKARKR PKCKKARKRP KCKRRKVAKK KC