PRTY2_CLUPA
ID PRTY2_CLUPA Reviewed; 30 AA.
AC P69009; P02335;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 25-MAY-2022, entry version 32.
DE RecName: Full=Protamine-YII;
DE AltName: Full=Clupeine-YII;
OS Clupea pallasii (Pacific herring).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Clupei; Clupeiformes; Clupeoidei;
OC Clupeidae; Clupea.
OX NCBI_TaxID=30724;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=4664740; DOI=10.1093/oxfordjournals.jbchem.a130035;
RA Suzuki K., Ando T.;
RT "Studies on protamines. XVI. The complete amino acid sequence of clupeine
RT YII.";
RL J. Biochem. 72:1419-1432(1972).
CC -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC during the haploid phase of spermatogenesis. They compact sperm DNA
CC into a highly condensed, stable and inactive complex.
CC -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC -!- TISSUE SPECIFICITY: Testis.
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DR PIR; A38052; CLHRY2.
DR AlphaFoldDB; P69009; -.
DR iPTMnet; P69009; -.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Chromosome; Developmental protein; Differentiation;
KW Direct protein sequencing; DNA condensation; DNA-binding; Nucleosome core;
KW Nucleus; Spermatogenesis.
FT PEPTIDE 1..30
FT /note="Protamine-YII"
FT /id="PRO_0000044306"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 30 AA; 4049 MW; 7F9BBB80F3ADA566 CRC64;
PRRRTRRASR PVRRRRPRRV SRRRRARRRR