ID   PRTZ1_SAROR             Reviewed;          34 AA.
AC   P25327;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Protamine-Z1/Z2;
DE   AltName: Full=Sardaine-Z1/Z2;
OS   Sarda orientalis (Striped bonito) (Pelamys orientalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Pelagiaria; Scombriformes; Scombridae; Sarda.
OX   NCBI_TaxID=8230;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Sperm;
RX   PubMed=1569040; DOI=10.1093/oxfordjournals.jbchem.a123730;
RA   Okamoto Y., Kuno K., Motohiro T., Nishi N., Muta E., Ota S.;
RT   "Primary structures of sardaines Z1 and Z2, protamines isolated from
RT   striped bonito (Sarda orientalis).";
RL   J. Biochem. 111:157-161(1992).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Testis.
CC   -!- MISCELLANEOUS: The sardaine Z1 sequence is shown.
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DR   PIR; JX0203; JX0203.
DR   PIR; JX0204; JX0204.
DR   AlphaFoldDB; P25327; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Chromosome; Developmental protein; Differentiation;
KW   Direct protein sequencing; DNA condensation; DNA-binding; Nucleosome core;
KW   Nucleus; Spermatogenesis.
FT   PEPTIDE         1..34
FT                   /note="Protamine-Z1/Z2"
FT                   /id="PRO_0000044847"
FT   REGION          1..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VARIANT         7
FT                   /note="S -> A (in protamine-Z2)"
SQ   SEQUENCE   34 AA;  4613 MW;  EEF72CED13D3C3DE CRC64;
     PRRRRRSSRP VRRRRRYRRS TAARRRRRVV RRRR