ID   PRTZ1_SCYCA             Reviewed;          51 AA.
AC   P08433;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Protamine-Z1;
DE   AltName: Full=Scylliorhinine-Z1;
OS   Scyliorhinus canicula (Small-spotted catshark) (Squalus canicula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC   Scyliorhinus.
OX   NCBI_TaxID=7830;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Testis;
RX   PubMed=3595601; DOI=10.1111/j.1432-1033.1987.tb11475.x;
RA   Berlot-Picard F., Vodjdani G., Doly J.;
RT   "Isolation and characterization of a cDNA clone encoding testis protamine
RT   Z1 from the dog-fish Scylliorhinus caniculus.";
RL   Eur. J. Biochem. 165:553-557(1987).
RN   [2]
RP   PROTEIN SEQUENCE OF 2-51.
RX   PubMed=6615852; DOI=10.1016/0167-4838(83)90031-6;
RA   Gusse M., Sautiere P., Chauviere M., Chevaillier P.;
RT   "Extraction, purification and characterization of the sperm protamines of
RT   the dog-fish Scylliorhinus caniculus.";
RL   Biochim. Biophys. Acta 748:93-98(1983).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Testis.
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DR   EMBL; X05611; CAA29099.1; -; mRNA.
DR   PIR; S00016; S00016.
DR   AlphaFoldDB; P08433; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Chromosome; Developmental protein; Differentiation;
KW   Direct protein sequencing; DNA condensation; DNA-binding; Nucleosome core;
KW   Nucleus; Spermatogenesis.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:6615852"
FT   CHAIN           2..51
FT                   /note="Protamine-Z1"
FT                   /id="PRO_0000106629"
FT   REGION          28..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   51 AA;  6475 MW;  0C6BA7F4678A8DB8 CRC64;
     MGSCKPKKKQ APCFLRRRHL RRLNVCKRDT SKTYRRRRHV RRLPKKRRRR C