PRT_PERFV
ID PRT_PERFV Reviewed; 34 AA.
AC P29629;
DT 01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1993, sequence version 1.
DT 25-MAY-2022, entry version 48.
DE RecName: Full=Protamine;
OS Perca flavescens (American yellow perch) (Morone flavescens).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Percoidei; Percidae; Percinae; Perca.
OX NCBI_TaxID=8167;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=1544489; DOI=10.1016/0014-5793(92)80239-d;
RA Chao H., Davies P.L.;
RT "Amino acid sequence of the unique protamine from yellow perch.";
RL FEBS Lett. 299:166-168(1992).
CC -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC during the haploid phase of spermatogenesis. They compact sperm DNA
CC into a highly condensed, stable and inactive complex.
CC -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC -!- TISSUE SPECIFICITY: Testis.
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DR PIR; S20439; S20439.
DR AlphaFoldDB; P29629; -.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Chromosome; Developmental protein; Differentiation;
KW Direct protein sequencing; DNA condensation; DNA-binding; Nucleosome core;
KW Nucleus; Spermatogenesis.
FT PEPTIDE 1..34
FT /note="Protamine"
FT /id="PRO_0000044835"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 34 AA; 4552 MW; EEFF4E0F87C6B2DE CRC64;
PRRRRHAARP VRRRRRTRRS SRVHRRRRAV RRRR