ID   PRUN2_XENTR             Reviewed;         316 AA.
AC   Q0IHU9;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Protein prune homolog 2;
DE   AltName: Full=BNIP2 motif-containing molecule at the C-terminal region 1;
GN   Name=Prune2; Synonyms=Bmcc1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; BC122960; AAI22961.1; -; mRNA.
DR   RefSeq; NP_001072592.1; NM_001079124.1.
DR   AlphaFoldDB; Q0IHU9; -.
DR   DNASU; 780047; -.
DR   GeneID; 780047; -.
DR   KEGG; xtr:780047; -.
DR   CTD; 158471; -.
DR   Xenbase; XB-GENE-989623; prune2.
DR   InParanoid; Q0IHU9; -.
DR   OrthoDB; 755773at2759; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0006915; P:apoptotic process; IBA:GO_Central.
DR   CDD; cd00170; SEC14; 1.
DR   Gene3D; 3.40.525.10; -; 1.
DR   InterPro; IPR022181; Bcl2-/adenovirus-E1B.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   Pfam; PF12496; BNIP2; 1.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   SMART; SM00516; SEC14; 1.
DR   SUPFAM; SSF52087; SSF52087; 1.
DR   PROSITE; PS50191; CRAL_TRIO; 1.
PE   2: Evidence at transcript level;
KW   Apoptosis; Cytoplasm; Reference proteome.
FT   CHAIN           1..316
FT                   /note="Protein prune homolog 2"
FT                   /id="PRO_0000274884"
FT   DOMAIN          128..285
FT                   /note="CRAL-TRIO"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00056"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          287..316
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   316 AA;  36048 MW;  FE1DC25DB4E7CF39 CRC64;
     MDIPLDAAEI RPEPPNSLDL NGSSTRKIKL TAPNINLSLD HSEGSILSDD NLDTPDELDI
     NVDDLDTPDE ADSFDYTGQD DQPALGEAVQ EDFESIQEYT AEEERADNRL WRTVVIGEQE
     QRIDMKVIEP YKKVISHGGY YGEGVNAIIV FAACFLPDSS RPDYNYVMEN LFLYVISTLE
     LMVAEDYMVV YLNGATPRRK MPGLGWMKKC YQMIDRRLRK NLKSFIIVHP SWFIRTILAL
     TRPFISSKFS SKIKYVSTLA ELSELIPMEY VHIPETIVKL DEELRESESP KAGCLPNEPE
     MNTLEEEFEN KMGDND