ID   PRY1_ARTBC              Reviewed;         309 AA.
AC   D4B327;
DT   09-DEC-2015, integrated into UniProtKB/Swiss-Prot.
DT   09-DEC-2015, sequence version 2.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=Probable pathogenesis-related protein ARB_02861 {ECO:0000305};
DE   AltName: Full=Wasp ves v 5 allergen homolog {ECO:0000305};
DE   Flags: Precursor;
GN   ORFNames=ARB_02861;
OS   Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton
OS   mentagrophytes).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=663331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4681 / CBS 112371;
RX   PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA   Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA   Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M.,
RA   Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O.,
RA   Schroeckh V., Hertweck C., Hube B., White T.C., Platzer M., Guthke R.,
RA   Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.;
RT   "Comparative and functional genomics provide insights into the
RT   pathogenicity of dermatophytic fungi.";
RL   Genome Biol. 12:R7.1-R7.16(2011).
CC   -!- FUNCTION: Secreted protein required for efficient export of lipids such
CC       as acetylated sterols. Acts in detoxification of hydrophobic compounds.
CC       {ECO:0000250|UniProtKB:P47032}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P47032}.
CC   -!- DOMAIN: The SCP domain is necessary and sufficient for lipid export and
CC       sterol-binding. {ECO:0000250|UniProtKB:P47032}.
CC   -!- ALLERGEN: May cause an allergic reaction in human. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CRISP family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EFE30323.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; ABSU01000031; EFE30323.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_003010963.1; XM_003010917.1.
DR   AlphaFoldDB; D4B327; -.
DR   SMR; D4B327; -.
DR   STRING; 663331.D4B327; -.
DR   EnsemblFungi; EFE30323; EFE30323; ARB_02861.
DR   GeneID; 9525080; -.
DR   KEGG; abe:ARB_02861; -.
DR   eggNOG; KOG3017; Eukaryota.
DR   HOGENOM; CLU_035730_5_0_1; -.
DR   Proteomes; UP000008866; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.33.10; -; 1.
DR   InterPro; IPR018244; Allrgn_V5/Tpx1_CS.
DR   InterPro; IPR014044; CAP_domain.
DR   InterPro; IPR035940; CAP_sf.
DR   InterPro; IPR001283; CRISP-related.
DR   PANTHER; PTHR10334; PTHR10334; 1.
DR   Pfam; PF00188; CAP; 1.
DR   PRINTS; PR00837; V5TPXLIKE.
DR   SMART; SM00198; SCP; 1.
DR   SUPFAM; SSF55797; SSF55797; 1.
DR   PROSITE; PS01009; CRISP_1; 1.
PE   3: Inferred from homology;
KW   Allergen; Glycoprotein; Lipid transport; Lipid-binding; Reference proteome;
KW   Secreted; Signal; Transport.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..309
FT                   /note="Probable pathogenesis-related protein ARB_02861"
FT                   /id="PRO_0000434918"
FT   DOMAIN          154..284
FT                   /note="SCP"
FT                   /evidence="ECO:0000250|UniProtKB:P47032"
FT   REGION          47..152
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        58..149
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        164
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ   SEQUENCE   309 AA;  32027 MW;  262BE27DBF0305FB CRC64;
     MKSSVLMTAL CVAGSLAAEQ ISPPNEVVVT AKKVVVVTTT VTTTIPCPTV IPTTSYKPEP
     TSKPPVIPPV PTSSAEPLPP PPVEPSTIPC PEPGTSTYAP PPPPPPPTSA PAPPAPPPPP
     PSSAPAPPAP PPSQPSQGPA PPPPPPGKDY KEVAGYHHNV HRSNHSAPAL TWSSALESSA
     RKLAESCNYG HDTSIDGGGY GQNIGYQSGY NNVAALLTEQ MYNEEAILFE GNYGNNNPSN
     FHSWGHFTQM VWIGTTHVGC FTAHCSNLGG QGSGGDAYYT VCNYSPPGNV LGQYAENVKP
     PKGQPVVTV