ID   PS1C2_MOUSE             Reviewed;         134 AA.
AC   Q80ZC9;
DT   21-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Psoriasis susceptibility 1 candidate gene 2 protein homolog;
DE   AltName: Full=Protein SPR1;
DE   Flags: Precursor;
GN   Name=Psors1c2; Synonyms=Spr1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Skin;
RX   PubMed=12930300; DOI=10.1034/j.1600-0625.2003.00048.x;
RA   Holm S.J., Carlen L.M., Mallbris L., Staehle-Baeckdahl M., O'Brien K.P.;
RT   "Polymorphisms in the SEEK1 and SPR1 genes on 6p21.3 associate with
RT   psoriasis in the Swedish population.";
RL   Exp. Dermatol. 12:435-444(2003).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
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DR   EMBL; AF484421; AAO49378.1; -; mRNA.
DR   RefSeq; NP_065601.2; NM_020576.2.
DR   AlphaFoldDB; Q80ZC9; -.
DR   STRING; 10090.ENSMUSP00000025273; -.
DR   PaxDb; Q80ZC9; -.
DR   PRIDE; Q80ZC9; -.
DR   DNASU; 57390; -.
DR   GeneID; 57390; -.
DR   KEGG; mmu:57390; -.
DR   CTD; 170680; -.
DR   MGI; MGI:1930025; Psors1c2.
DR   eggNOG; ENOG502QQEE; Eukaryota.
DR   InParanoid; Q80ZC9; -.
DR   OMA; LPDDPWP; -.
DR   BioGRID-ORCS; 57390; 3 hits in 73 CRISPR screens.
DR   PRO; PR:Q80ZC9; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; Q80ZC9; protein.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR029271; SPR1.
DR   PANTHER; PTHR31853; PTHR31853; 1.
DR   Pfam; PF15356; SPR1; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..134
FT                   /note="Psoriasis susceptibility 1 candidate gene 2 protein
FT                   homolog"
FT                   /id="PRO_0000022160"
FT   REGION          18..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        39..70
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        77..113
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   134 AA;  14414 MW;  1DEC862AD49A0A32 CRC64;
     MLTWKLLGLL VLCLCAGGIS GNGDPSPGST DTHEEEDSPP LPLGPPIPGD PWPGAPPLFD
     EPPPPGSNRP WRDLPDSGAW PPKPPSTDPP KPPLPDDPWP AGTQPPENPW PPAPEMDHES
     QEEPDLDPPQ EEYR