ID   PS1C2_PANTR             Reviewed;         136 AA.
AC   Q7YR45; Q1XI10;
DT   21-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Psoriasis susceptibility 1 candidate gene 2 protein homolog;
DE   AltName: Full=Protein SPR1;
DE   Flags: Precursor;
GN   Name=PSORS1C2; Synonyms=SPR1;
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12799463; DOI=10.1073/pnas.1230533100;
RA   Anzai T., Shiina T., Kimura N., Yanagiya K., Kohara S., Shigenari A.,
RA   Yamagata T., Kulski J.K., Naruse T.K., Fujimori Y., Fukuzumi Y.,
RA   Yamazaki M., Tashiro H., Iwamoto C., Umehara Y., Imanishi T., Meyer A.,
RA   Ikeo K., Gojobori T., Bahram S., Inoko H.;
RT   "Comparative sequencing of human and chimpanzee MHC class I regions unveils
RT   insertions/deletions as the major path to genomic divergence.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7708-7713(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16702430; DOI=10.1534/genetics.106.057034;
RA   Shiina T., Ota M., Shimizu S., Katsuyama Y., Hashimoto N., Takasu M.,
RA   Anzai T., Kulski J.K., Kikkawa E., Naruse T., Kimura N., Yanagiya K.,
RA   Watanabe A., Hosomichi K., Kohara S., Iwamoto C., Umehara Y., Meyer A.,
RA   Wanner V., Sano K., Macquin C., Ikeo K., Tokunaga K., Gojobori T.,
RA   Inoko H., Bahram S.;
RT   "Rapid evolution of major histocompatibility complex class I genes in
RT   primates generates new disease alleles in humans via hitchhiking
RT   diversity.";
RL   Genetics 173:1555-1570(2006).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
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DR   EMBL; BA000041; BAC78169.1; -; Genomic_DNA.
DR   EMBL; AB210147; BAE92756.1; -; Genomic_DNA.
DR   EMBL; AB210148; BAE92760.1; -; Genomic_DNA.
DR   RefSeq; NP_001038970.1; NM_001045505.1.
DR   AlphaFoldDB; Q7YR45; -.
DR   PaxDb; Q7YR45; -.
DR   GeneID; 462554; -.
DR   KEGG; ptr:462554; -.
DR   CTD; 170680; -.
DR   eggNOG; ENOG502QQEE; Eukaryota.
DR   InParanoid; Q7YR45; -.
DR   OrthoDB; 1622929at2759; -.
DR   Proteomes; UP000002277; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR029271; SPR1.
DR   PANTHER; PTHR31853; PTHR31853; 1.
DR   Pfam; PF15356; SPR1; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..136
FT                   /note="Psoriasis susceptibility 1 candidate gene 2 protein
FT                   homolog"
FT                   /id="PRO_0000022161"
FT   REGION          20..136
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        43..117
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        118..136
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   136 AA;  15084 MW;  31D44EFED8ADF8A7 CRC64;
     MILNWKLLGI LVLCLHTRGI SGSEDHPSHP PAEDREEAGS PTLPQGPPVP GDPWPGAPPL
     FEDPPPPHPS PPWRDLPETG VWPPEPPRTD PPQPPRPDDP WPAGPQPPEN PWPPAPEVDH
     RPQEEPDLDP PREEYR