PSA6_SOYBN
ID PSA6_SOYBN Reviewed; 246 AA.
AC O48551;
DT 08-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 2.
DT 25-MAY-2022, entry version 109.
DE RecName: Full=Proteasome subunit alpha type-6;
DE AltName: Full=20S proteasome alpha subunit A;
DE AltName: Full=20S proteasome subunit alpha-1;
DE AltName: Full=Proteasome iota subunit;
GN Name=PAA1;
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Tang Y., Skorupska H.T., Abbott A.G.;
RT "Characterization of proteasomal iota subunit gene of soybean, Glycine max
RT (L.) Merr.";
RL Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: The proteasome is a multicatalytic proteinase complex which
CC is characterized by its ability to cleave peptides with Arg, Phe, Tyr,
CC Leu, and Glu adjacent to the leaving group at neutral or slightly basic
CC pH. The proteasome has an ATP-dependent proteolytic activity (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: The 26S proteasome consists of a 20S proteasome core and two
CC 19S regulatory subunits. The 20S proteasome core is composed of 28
CC subunits that are arranged in four stacked rings, resulting in a
CC barrel-shaped structure. The two end rings are each formed by seven
CC alpha subunits, and the two central rings are each formed by seven beta
CC subunits. The catalytic chamber with the active sites is on the inside
CC of the barrel (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the peptidase T1A family. {ECO:0000255|PROSITE-
CC ProRule:PRU00808}.
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DR EMBL; AF034572; AAC28135.1; -; mRNA.
DR PIR; T06142; T06142.
DR AlphaFoldDB; O48551; -.
DR SMR; O48551; -.
DR STRING; 3847.GLYMA12G22340.1; -.
DR MEROPS; T01.971; -.
DR PRIDE; O48551; -.
DR ProMEX; O48551; -.
DR eggNOG; KOG0182; Eukaryota.
DR HOGENOM; CLU_035750_4_1_1; -.
DR InParanoid; O48551; -.
DR Proteomes; UP000008827; Unplaced.
DR Genevisible; O48551; GM.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005839; C:proteasome core complex; IBA:GO_Central.
DR GO; GO:0019773; C:proteasome core complex, alpha-subunit complex; ISS:UniProtKB.
DR GO; GO:0010498; P:proteasomal protein catabolic process; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR CDD; cd03754; proteasome_alpha_type_6; 1.
DR Gene3D; 3.60.20.10; -; 1.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR InterPro; IPR023332; Proteasome_alpha-type.
DR InterPro; IPR000426; Proteasome_asu_N.
DR InterPro; IPR001353; Proteasome_sua/b.
DR InterPro; IPR034642; Proteasome_subunit_alpha6.
DR Pfam; PF00227; Proteasome; 1.
DR Pfam; PF10584; Proteasome_A_N; 1.
DR SMART; SM00948; Proteasome_A_N; 1.
DR SUPFAM; SSF56235; SSF56235; 1.
DR PROSITE; PS00388; PROTEASOME_ALPHA_1; 1.
DR PROSITE; PS51475; PROTEASOME_ALPHA_2; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Nucleus; Proteasome; Reference proteome.
FT CHAIN 1..246
FT /note="Proteasome subunit alpha type-6"
FT /id="PRO_0000124138"
SQ SEQUENCE 246 AA; 27392 MW; B9CE2F42DD075981 CRC64;
MSRGSGGGYN RHITIFSPEG RLFQVEYAFK AVKAAGITSI GVRGKDSICV VTHKKVPDKL
LDNTSVTHLF PITKYLGLLA TGMTADARTL VQQARNEAAE FRFTYGYEMP VDVLAKWIAD
KSQVYTQHAY MRPLGVVAMV LGIDDEYGPQ LYKCDPAGHY FGHKATSAGL KDQEAINFLE
KKMKNDPSFT YEETVQTAIS ALQSVLQEDF KATEIEVGVV RKDNPEFRVL TTDEIDEHLT
AISERD
